Paraformaldehyde-Glutaraldehyde Mixed Fixative (4%/0.5%) is a classic aldehyde-based mixed fixative specifically designed for electron microscopy (transmission electron microscopy) sample preparation. This fixative is composed of 4% paraformaldehyde and 0.5% glutaraldehyde in phosphate buffer (pH ~7.4). Its core advantage lies in combining the excellent membrane penetration of paraformaldehyde with the rapid and stable crosslinking capability of glutaraldehyde for protein ultrastructure. This effectively prevents autolysis and maximally preserves the native state of organelles and subcellular structures, making it an ideal choice for preserving sample ultrastructure in electron microscopic observation. It should be noted that the fixation mechanism of this solution is primarily directed at proteins; therefore, it is not suitable for fixing nucleic acids or polysaccharides.
危险品化学品经营许可证（带存储）