| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| P638962-1mg |
1mg |
现货  |
| |
| P638962-5mg |
5mg |
现货 |
|
| 别名 | Pacific Blue™琥珀酰亚胺酯 | 3-羧基-6,8-二氟-7-羟基香豆素琥珀酰亚胺酯 |
|---|---|
| 英文别名 | Ocean Blue, SE | PB succiniMidyl ester | (2,5-dioxopyrrolidin-1-yl) 6,8-difluoro-7-hydroxy-2-oxochromene-3-carboxylate | 3-Carboxy-6,8-difluoro-7-hydroxycoumarin succinimidyl ester | 6,8-difluoro-7-hydroxy-2-oxo-2H-chromene-3-carboxylic acid succinimidyl |
| 规格或纯度 | Ex:404nm, Em:455nm, ≥98% |
| 英文名称 | Pacific Blue Succinimidyl Ester |
| 储存温度 | 避光,-20°C储存 |
| 运输条件 | 超低温冰袋运输 |
| 产品介绍 |
Pacific blue succinimidyl ester is an N-hydroxysuccinimide ester derived from 6,8-difluoro-7-hydroxycoumarin-3-carboxylic acid (pacific blue). A fluorescent dye of excitation wavelength 403 nm and emission wavelength 455 nm. It has a role as a fluorochrome. It is a hydroxycoumarin, an organofluorine compound and a N-hydroxysuccinimide ester. It is functionally related to a pacific blue. |
| IUPAC Name | (2,5-dioxopyrrolidin-1-yl) 6,8-difluoro-7-hydroxy-2-oxochromene-3-carboxylate |
|---|---|
| INCHI | InChI=1S/C14H7F2NO7/c15-7-4-5-3-6(13(21)23-12(5)10(16)11(7)20)14(22)24-17-8(18)1-2-9(17)19/h3-4,20H,1-2H2 |
| InChi Key | NZYXABPVYJRICY-UHFFFAOYSA-N |
| Canonical SMILES | C1CC(=O)N(C1=O)OC(=O)C2=CC3=CC(=C(C(=C3OC2=O)F)O)F |
| Isomeric SMILES | C1CC(=O)N(C1=O)OC(=O)C2=CC3=CC(=C(C(=C3OC2=O)F)O)F |
| PubChem CID | 56927770 |
| 分子量 | 339.20 |
| 溶解性 | DMSO(Dimethylsulfoxide) |
|---|---|
| 敏感性 | 对光线敏感；对湿度敏感 |
| 分子量 | 339.200 g/mol |
| XLogP3 | 0.900 |
| 氢键供体数Hydrogen Bond Donor Count | 1 |
| 氢键受体数Hydrogen Bond Acceptor Count | 9 |
| 可旋转键计数Rotatable Bond Count | 3 |
| 精确质量Exact Mass | 339.019 Da |
| 单同位素质量Monoisotopic Mass | 339.019 Da |
| 拓扑极表面积Topological Polar Surface Area | 110.000 Ų |
| 重原子数Heavy Atom Count | 24 |
| 形式电荷Formal Charge | 0 |
| 复杂度Complexity | 633.000 |
| 同位素原子数Isotope Atom Count | 0 |
| 定义的原子立体中心计数Defined Atom Stereocenter Count | 0 |
| 未定义的原子立体中心计数Undefined Atom Stereocenter Count | 0 |
| 定义的键立体中心计数Defined Bond Stereocenter Count | 0 |
| 未定义的键立体中心计数Undefined Bond Stereocenter Count | 0 |
| 所有立体化学键的总数The total count of all stereochemical bonds | 0 |
| 共价键合单元计数Covalently-Bonded Unit Count | 1 |
| 1. Krutzik PO, Nolan GP. Fluorescent cell barcoding in flow cytometry allows high-throughput drug screening and signaling profiling.. Nat Methods, [PMID:16628206] [http://pubmed.ncbi.nlm.nih.gov/16628206] |
| 2. Knowles MK, Guenza MG, Capaldi RA, Marcus AH. Cytoskeletal-assisted dynamics of the mitochondrial reticulum in living cells.. Proc Natl Acad Sci U S A, [PMID:12417764] [http://pubmed.ncbi.nlm.nih.gov/12417764] |
| 3. Marras SA, Kramer FR, Tyagi S. Efficiencies of fluorescence resonance energy transfer and contact-mediated quenching in oligonucleotide probes.. Nucleic Acids Res, [PMID:12409481] [http://pubmed.ncbi.nlm.nih.gov/12409481] |
| 4. Liu L, Guo Z, Tieu Q, Castle A, Castle D. Role of secretory carrier membrane protein SCAMP2 in granule exocytosis.. Mol Biol Cell, [PMID:12475951] [http://pubmed.ncbi.nlm.nih.gov/12475951] |
| 5. Roux MM, Pain A, Klimpel KR, Dhar AK. The lipopolysaccharide and beta-1,3-glucan binding protein gene is upregulated in white spot virus-infected shrimp (Penaeus stylirostris).. J Virol, [PMID:12072514] [http://pubmed.ncbi.nlm.nih.gov/12072514] |
| 6. Van Dover CL, German CR, Speer KG, Parson LM, Vrijenhoek RC. Evolution and biogeography of deep-sea vent and seep invertebrates.. Science, [PMID:11847331] [http://pubmed.ncbi.nlm.nih.gov/11847331] |
| 7. Sun WC, Gee KR, Haugland RP. Synthesis of novel fluorinated coumarins: excellent UV-light excitable fluorescent dyes.. Bioorg Med Chem Lett, [PMID:9873685] [http://pubmed.ncbi.nlm.nih.gov/9873685] |
| 8. Baart EB, Martini E, Van Opstal D. Screening for aneuploidies of ten different chromosomes in two rounds of FISH: a short and reliable protocol.. Prenat Diagn, [PMID:15614916] [http://pubmed.ncbi.nlm.nih.gov/15614916] |
| 9. Medler S. Comparative trends in shortening velocity and force production in skeletal muscles.. Am J Physiol Regul Integr Comp Physiol, [PMID:12121850] [http://pubmed.ncbi.nlm.nih.gov/12121850] |
| 10. Saavedra-Lozano J, Cao Y, Callison J, Sarode R, Sodora D, Edgar J, Hatfield J, Picker L, Peterson D, Ramilo O, Vitetta ES. An anti-CD45RO immunotoxin kills HIV-latently infected cells from individuals on HAART with little effect on CD8 memory.. Proc Natl Acad Sci U S A, [PMID:14983037] [http://pubmed.ncbi.nlm.nih.gov/14983037] |
| 11. Cox WG, Singer VL,. Fluorescent DNA hybridization probe preparation using amine modification and reactive dye coupling.. Biotechniques, [PMID:14740493] [http://pubmed.ncbi.nlm.nih.gov/14740493] |
| 12. Kohlsdorf T, James RS, Carvalho JE, Wilson RS, Dal Pai-Silva M, Navas CA. Locomotor performance of closely related Tropidurus species: relationships with physiological parameters and ecological divergence.. J Exp Biol, [PMID:14978059] [http://pubmed.ncbi.nlm.nih.gov/14978059] |
| 13. Lima RN, Kültz D. Laser scanning cytometry and tissue microarray analysis of salinity effects on killifish chloride cells.. J Exp Biol, [PMID:15073205] [http://pubmed.ncbi.nlm.nih.gov/15073205] |
| 14. Kalland ME, Oberprieler NG, Vang T, Taskén K, Torgersen KM,. T cell-signaling network analysis reveals distinct differences between CD28 and CD2 costimulation responses in various subsets and in the MAPK pathway between resting and activated regulatory T cells.. J Immunol, [PMID:22013130] [http://pubmed.ncbi.nlm.nih.gov/22013130] |
| 15. Clutter MR, Heffner GC, Krutzik PO, Sachen KL, Nolan GP,. Tyramide signal amplification for analysis of kinase activity by intracellular flow cytometry.. Cytometry A, [PMID:20824632] [http://pubmed.ncbi.nlm.nih.gov/20824632] |
| 16. Al Attar HA, Monkman AP,. FRET and competing processes between conjugated polymer and dye substituted DNA strands: a comparative study of probe selection in DNA detection.. Biomacromolecules, [PMID:19334782] [http://pubmed.ncbi.nlm.nih.gov/19334782] |
| 17. Kumari S,Wälchli S,Fallang LE,Yang W,Lund-Johansen F,Schumacher TN,Olweus J. Alloreactive cytotoxic T cells provide means to decipher the immunopeptidome and reveal a plethora of tumor-associated self-epitopes.. [PMID:24344295] [http://pubmed.ncbi.nlm.nih.gov/24344295] |
| 18. Irish JM, Myklebust JH, Alizadeh AA, Houot R, Sharman JP, Czerwinski DK, Nolan GP, Levy R,. B-cell signaling networks reveal a negative prognostic human lymphoma cell subset that emerges during tumor progression.. Proc Natl Acad Sci U S A, [PMID:20543139] [http://pubmed.ncbi.nlm.nih.gov/20543139] |
| 19. Chiesl TN, Chu WK, Stockton AM, Amashukeli X, Grunthaner F, Mathies RA,. Enhanced amine and amino acid analysis using Pacific Blue and the Mars Organic Analyzer microchip capillary electrophoresis system.. Anal Chem, [PMID:19245228] [http://pubmed.ncbi.nlm.nih.gov/19245228] |
| 20. Thurber GM,Reiner T,Yang KS,Kohler RH,Weissleder R. Effect of Small-Molecule Modification on Single-Cell Pharmacokinetics of PARP Inhibitors.. [PMID:24552776] [http://pubmed.ncbi.nlm.nih.gov/24552776] |
| 21. Krutzik PO, Crane JM, Clutter MR, Nolan GP,. High-content single-cell drug screening with phosphospecific flow cytometry.. Nat Chem Biol, [PMID:18157122] [http://pubmed.ncbi.nlm.nih.gov/18157122] |
| 22. Johnston IA, Fernández DA, Calvo J, Vieira VL, North AW, Abercromby M, Garland T. Reduction in muscle fibre number during the adaptive radiation of notothenioid fishes: a phylogenetic perspective.. J Exp Biol, [PMID:12819266] [http://pubmed.ncbi.nlm.nih.gov/12819266] |
首页
400-620-6333
B2526319