PKI (14-24)amide TFA is a potent PKA inhibitor. PKI (14-24)amide strongly inhibited cyclic AMP-dependent protein kinase activity in the cell homogenate.
In Vitro
PKI (14-24)amide TFA does not inhibit cyclic AMP-evoked amylase release from saponin-permeabilized cells. MCE has not independently confirmed the accuracy of these methods. They are for reference only.