PERK-IN-2 is a potent PERK inhibitor with an IC 50 of 0.2 nM
In Vitro
PERK-IN-2 (0.03-0.3 μM; 2 hours) inhibits PERK autophosphorylation in A459 cells with IC 50 value ranging from 0.03−0.1 μM. MCE has not independently confirmed the accuracy of these methods. They are for reference only. Cell Viability AssayCell Line: A459 cells Concentration: 0.03 μM, 0.1 μM, 0.3 μM Incubation Time: 2 hours Result: Inhibited PERK autophosphorylation in A459 cells.