槲皮素,二水

CAS: 6151-25-3 货号: Q408870 分子式: C₁₅H₁₀O₇·2H₂O 分子量: 338.27 Beilstein号: 317313 EC号: 612-158-3 PubChem CID: 5284452

概述规格名称和识别符技术文档高级数据关联靶点（人）质检证书（CoA,COO,BSE/TSE 和分析图谱) 化学和物理性质安全和危险性（GHS）此产品的引用文献技术文档和文章引用文献溶液计算器

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为什么选择此级别

Moligand™ 级，适用于对基线干扰要求严格的色谱和分析工作流程。

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储存与运输

-80℃储存。特低温运输。请查阅批次 COA 获取详细规格。

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质量文档

SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。

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文献证明

在色谱分析、有机合成和交叉偶联反应领域已被 10 篇同行评审文献引用。

概述

热至95-97℃变为无水物。312-314℃分解。1g溶于290ml无水乙醇、23ml沸乙醇，溶于冰乙酸，溶于碱液呈黄色，几乎不溶于水。醇溶液味苦。最大吸收波长(乙醇中)258、275nm(logε 2.75、2.75)。有毒，半数致死量(小鼠，经口)160mg/kg。槲皮素是一种抗锥体和抗利尿剂的化合物。槲皮素是有名的生物类黄酮，有报道表明它能影响体内肿瘤生长。槲皮素对杜氏利什曼原虫的无鞭毛阶段具有杀虫作用。有机灵敏试剂，铝的荧光测定，铁、锡、锆的光度测定。生化试剂，线粒体腺苷三磷酸酯酶的抑制剂。医药。与表氯醇(3-氯-1,2-环氧丙烷)混合形成环氧树脂。槲皮素水合物被用作利什曼原虫黄酮醇，用于研究槲皮素、槲皮素和异槲皮苷对来源于亚马孙利什曼原虫的重组精氨酸酶的抑制作用。

Information

Quercetin (Sophoretin), a polyphenolic flavonoid found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine, is utilized in many different cultures for their nervous system and anticancer effects. Quercetin (dihydrate), a
In vitro

Quercetin, a polyphenolic flavonoid found in a wide variety of plant-based foods, such as apples, onions, berries, and red wine, is utilized in many different cultures for their nervous system and anticancer effects. The pharmacological activities of quercetin that modulate antioxidation/oxidation/kinase-signaling pathways might be differentially elicited in neurons compared with malignant cells, ultimately promoting cell survival or death in a cell type- and metabolism-specific manner. Whereas the broad antioxidation and anti-inflammatory activities of quercetin are important for neuronal survival, the oxidative, kinase- and cell cycle-inhibitory, apoptosis-inducing effects of quercetin are essential for its anticancer effects.

In vivo

LD50: Mice 159mg/kg (i.g.)
Cell Data

cell lines：

Concentrations：Concentrations:

Incubation Time：Incubation Time:

Powder Purity:≥95%

规格

英文别名

Sophoretin | 4H-1-Benzopyran-4-one, 2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-, hydrate (1:2)

规格或纯度

Moligand™, 10mM in DMSO

英文名称

Quercetin Dihydrate

生化机理

槲皮素（槐黄素）是一种多酚类黄酮，存在于苹果、洋葱、浆果和红葡萄酒等多种植物性食物中，在许多不同的文化中都被用来治疗神经系统疾病和抗癌。槲皮素（二水合物）是一种天然类黄酮，是重组 SIRT1 的刺激剂和 PI3K 抑制剂，对 PI3K γ、PI3K δ 和 PI3K β 的 IC50 分别为 2.4 μM、3.0 μM 和 5.4 μM。

储存条件

-80℃储存

运输条件

特低温运输

名称和识别符

EC号

612-158-3

分子类型

小分子

Isomeric SMILES

C1=CC(=C(C=C1C2=C(C(=O)C3=C(C=C(C=C3O2)O)O)O)O)O.O.O

关联CAS

849061-97-8

PubChem CID

5284452

UN Number

2811

分子量

338.27

Beilstein号

317313

技术文档

📋 安全数据表 (SDS)

全面的危险、操作、储存及法规合规文件。

下载 SDS →

✅ 分析证书 (COA)

批次质量数据。输入批号以获取对应 COA。

查询 COA →

📊 产品数据表

产品规格和应用的快速参考摘要。

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🔬 规格说明书

该级别的完整质量属性和验收标准。

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高级数据

关联靶点（人）

CYP1A2 Tchem 细胞色素 P450 1A2(Cytochrome P450 1A2) (1 活性数据)

点击查看靶蛋白信息： CYP1A2

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

CYP2C9 Tchem 细胞色素 P450 2C9(Cytochrome P450 2C9) (1 活性数据)

点击查看靶蛋白信息： CYP2C9

活性类型	活性值-log(M)	作用机制	期刊	参考文献(PubMed IDs)

化学和物理性质

溶解性

Solubility (25°C) In vitro DMSO: 67 mg/mL (197.96 mM); Ethanol: -1 mg/mL

熔点

>300°C

安全和危险性（GHS）

象形图

GHS06

信号词

Danger

危险声明

H301: 吞咽会中毒

预防措施声明

P321: 特殊处理（请参阅此标签上的...）。

P405: 密闭存放

P501: 将内容物/容器处理到。。。

P264: 处理后要彻底洗手。

P270: 使用本产品时，请勿进食、饮水或吸烟。

P330: 漱口

P301+P316: 如果吞咽：立即寻求紧急医疗救助。

WGK Germany

RTECS

LK8950000

质检证书（CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):

输入批号以搜索分析图谱:

技术文档和文章

糖基化对天然产物亲水—亲脂分配与溶解行为的影响——以槲皮素、异槲皮苷和芦丁为例

目录：技术文章

探索主题:

糖基化槲皮素异槲皮苷芦丁

Effect of Glycosylation on the Hydrophilic–Lipophilic Partitioning and Solubility Behavior of Natural Products—Quercetin, Isoquercitrin, and Rutin as Examples

目录：技术文章

探索主题:

Glycosylation quercetin isoquercitrin rutin

此产品的引用文献

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引用文献

1. Siyu Gui, Weiwei Tang, Zhihao Huang, Xinchen Wang, Siyin Gui, Xiang Gao, Duncheng Xiao, Liming Tao, Zhengxuan Jiang, Xianwen Wang. (2023) Ultrasmall Coordination Polymer Nanodots Fe-Quer Nanozymes for Preventing and Delaying the Development and Progression of Diabetic Retinopathy. ADVANCED FUNCTIONAL MATERIALS, [10.1002/adfm.202300261]
2. Do Hee Kim, Eun Woo Jeong, Youjin Baek, Hyeon Gyu Lee. (2023) Development of propolis extract-loaded nanoparticles with chitosan and hyaluronic acid for improving solubility and stability. LWT-FOOD SCIENCE AND TECHNOLOGY, [10.1016/j.lwt.2023.114738]
3. Jinhao Zhao, Minmin Liang, Zhongyan Wang, Yanyan Zhao, Jingli Cheng, Yongjun Du. (2022) Evaluation and optimization of blends for attracting Trichogramma dendrolimi based on semiochemicals mediating tritrophic interactions in the orchard habitat. BIOLOGICAL CONTROL, [10.1016/j.biocontrol.2022.104998]
4. Jian-Feng Zhou, Wen-Jun Wang, Zhong-Ping Yin, Guo-Dong Zheng, Ji-Guang Chen, Jing-En Li, Ling-Li Chen, Qing-Feng Zhang. (2021) Quercetin is a promising pancreatic lipase inhibitor in reducing fat absorption in vivo. Food Bioscience, [10.1016/j.fbio.2021.101248]
5. Chang Ping Yang, Li He, Cheng Zhi Huang, Yuan Fang Li, Shu Jun Zhen. (2020) Continuous singlet oxygen generation for persistent chemiluminescence in Cu-MOFs-based catalytic system. TALANTA, [PMID:33076101] [10.1016/j.talanta.2020.121498]
6. Xu Lujing, Shu Tong, Liu Songbai. (2019) Simplified Quantification of Representative Bioactives in Food Through TLC Image Analysis. Food Analytical Methods, 12 (12): (2886-2894). [10.1007/s12161-019-01645-x]
7. Xu Ma, Hong Su, Yongming Liu, Fenghua Chen, Rongrong Xue. (2025) Superior solubility of anhydrous quercetin and polymer physical mixtures compared to amorphous solid dispersions. RSC Advances, 15 (12): (9348-9358). [PMID:40151530] [10.1039/D4RA08796H]
8. Zhou Jian-Feng, Xu Hai-Xia, Yin Zhong-Ping, Chen Ji-Guang, Zhang Qing-Feng. (2024) The combination effects of quercetin on starch and digestive enzymes reduce postprandial blood glucose in rats. EUROPEAN FOOD RESEARCH AND TECHNOLOGY, [10.1007/s00217-023-04455-y]
9. Lei Wang, Sipeng Yu, Ju Wang, Qiuping Wang, Yu Mao, Lei Zheng. (2025) Manganese-doped carbon nanospheres with robust peroxidase-like activity for the colorimetric detection of total antioxidant capacity. FOOD CHEMISTRY, [PMID:40252442] [10.1016/j.foodchem.2025.144349]
10. Kaiqiang Yang, Junlei Liu, Yiming Yang, Wenying Li. (2026) Engineering the Microenvironment of Cu-MOF Nanozyme via Modulating Ligand Hydrophobicity for Array-Based Profiling of Phenolic Acids in Natural Products. TALANTA, [PMID:41519042] [10.1016/j.talanta.2026.129350]