计算溶液所需的质量、体积或浓度。
为什么选择此级别
提供 ≥95% 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。
储存与运输
2-8°C储存。低温运输 。请查阅批次 COA 获取详细规格。
质量文档
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
文献证明
在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
概述
Ro 363 hydrochloride, an effective inotropic stimulant, is a potent and highly selective β1-adrenoceptor agonist. Ro 363 hydrochloride is a cardiovascular modulator that reduces diastolic blood pressure and pronounces increases in myocardial contractility .
In Vitro
Isolated perfused heart preparations from guinea-pigs developed arrhythmic contractions following the administration of Ro 363 in doses producing 70-100% of its maximal chronotropic responses. In spontaneously contracted tracheal preparations from the guinea-pig, RO 363 is a full agonist and is approximately half as potent as (-)-Isoprenaline. These effects of RO 363 are due to the activation of a population of β1-receptors in the tissue since RO 363 and (-)-Isoprenaline have the same relative potencies in trachea, cardiac and ileal preparations. MCE has not independently confirmed the accuracy of these methods. They are for reference only.
In Vivo
In chloralose-anaesthetized cats, Ro 363, when compared to epinephrine (adrenaline), is essentially devoid of arrhythmogenic activity in animals in which cardiac sensitization is induced by U-0882 or halothane . MCE has not independently confirmed the accuracy of these methods. They are for reference only.
Form:Solid
规格
别名
Ro363盐酸盐
规格或纯度
≥95%
英文名称
Ro 363 hydrochloride
生化机理
Ro 363 盐酸盐是一种有效的肌力兴奋剂，是一种强效、高选择性的 β1 肾上腺素受体激动剂。Ro 363 盐酸盐是一种心血管调节剂，可降低舒张压并增强心肌收缩力。
储存条件
2-8°C储存
运输条件
低温运输
作用类型
激动剂
纯度
≥95%
名称和识别符
分子类型
小分子
分子量
399.87
技术文档
高级数据
化学和物理性质
溶解性
DMSO : 125 mg/mL (312.60 mM; Need ultrasonic) H2O : 50 mg/mL (125.04 mM; Need ultrasonic)
质检证书(CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:
溶液计算器
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