Measured by its ability to inhibit Recombinant Human Coagulation Factor II/Thrombin cleavage of a fluorogenic peptide substrate Boc-VPR-AMC. The IC50 value is <5 nM, as measured under the described conditions.
Most important serine protease inhibitor in plasma that regulates the blood coagulation cascade. AT-III inhibits thrombin as well as factors IXa, Xa and XIa. Its inhibitory activity is greatly enhanced in the presence of heparin.
规格
产品名称
Recombinant Human Serpin C1/Antithrombin-III Protein
别名
重组人Serpin C1/Antithrombin-III蛋白 | 重组人抗凝血酶蛋白
英文别名
AT3 | Antithrombin-III | ATIII | antithrombin III | MGC22579 | serine (or cysteine) proteinase inhibitor, clade C (antithrombin), member 1 | serine-cysteine proteinase inhibitor clade C member 1 | Serpin C1 | serpin peptidase inhibitor, clade C (antithrom
规格或纯度
无动物源,无载体,生物活性,ActiBioPure™,His标签,≥95%(SDS-PAGE)
生物活性
Measured by its ability to inhibit Recombinant Human Coagulation Factor II/Thrombin cleavage of a fluorogenic peptide substrate Boc-VPR-AMC. The IC50 value is <5 nM, as measured under the described conditions.
53 - 60 kDa, under reducing conditions; 50 - 57 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH7.4.
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human Serpin C1/Antithrombin-III Protein (rp142864) - SDS-PAGE 3 μg/lane of Recombinant Human Serpin C1/Antithrombin-III Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 53 - 60 kDa under reducing condition and 50 - 57 kDa under non-reducing condition.
ZJ24F1216173
危险品化学品经营许可证（带存储）