Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 20 μg/ml, corresponding to a specific activity of > 50 IU/mg.
Function Selectively promotes the survival of dopaminergic neurons of the ventral mid-brain. Modulates GABAergic transmission to the dopaminergic neurons of the substantia nigra. Enhances spontaneous, as well as evoked, GABAergic inhibitory postsynaptic currents in dopaminergic neurons (By similarity). Inhibits cell proliferation and endoplasmic reticulum (ER) stress-induced cell death.
Post-translational May contain sialic acid residues.
规格
产品名称
Recombinant Human ARMET/ARP Protein
别名
重组人 ARMET/ARP 蛋白 | 重组人类 ARMET/ARP 蛋白
英文别名
Arginine rich mutated in early stage tumors | Arginine rich protein | Arginine-rich protein | ARMET | ARMET protein | ARP | Manf | MANF_HUMAN | Mesencephalic astrocyte derived neurotrophic factor | Mesencephalic astrocyte-derived neurotrophic factor | MGC
Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 20 μg/ml, corresponding to a specific activity of > 50 IU/mg.
Lyophilized from a 0.2 µm filtered concentrated solution in PBS, pH 7.4.
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Recombinant Human ARMET/ARP Protein (rp142973)-Protein Bioactivity Fully biologically active when compared to standard. The ED50 as determined by a cell proliferation assay using rat C6 cells is less than 20 μg/mL, corresponding to a specific activity of > 50 IU/mg.
Recombinant Human ARMET/ARP Protein (rp142973)-SDS-PAGE Recombinant Human ARMET/ARP Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining. Showing a band at 18.2 kDa under reducing conditions and 16.8 kDa under non-reducing conditions.
ZJ23F0600497
危险品化学品经营许可证（带存储）