Measured by the ability of the immobilized protein to support the adhesion of the MCF‑7 human breast cancer cells. The ED50 of this effect is 0.06-0.6 μg/mL.
Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment.
规格
产品名称
Recombinant Human IBSP/Sialoprotein II Protein
别名
骨涎蛋白(BSP)活性蛋白
英文别名
Bone sialoprotein II | BSP II | Cell-binding sialoprotein | Integrin-binding sialoprotein | Bone sialoprotein 2 | BNSP | Bone sialoprotein | BSP 2 | BSP II | BSP | BSP2 | BSPII | BSP-II | Cell binding sialoprotein | IBSP | Integrin binding sialoprotein |
Measured by the ability of the immobilized protein to support the adhesion of the MCF‑7 human breast cancer cells. The ED50 of this effect is 0.06-0.6 μg/mL.
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH 7.4
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。复溶后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human IBSP/Sialoprotein II Protein (rp143342) - SDS-PAGE 2 μg/lane of Recombinant Human IBSP/Sialoprotein II Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 70 - 110 kDa. The protein has a calculated MW of 35 kDa. The protein migrates as 70 - 110 kDa under reducing (R) and non-reducing (N) conditions due to glycosylation.
Recombinant Human IBSP/Sialoprotein II Protein (rp143342) - SDS-PAGE 2 μg/lane of Recombinant Human IBSP/Sialoprotein II Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 70 - 105 kDa. IBSP/Sialoprotein II is a highly glycosylated bone matrix protein, and its glycosylation modifications play a critical role in its biological functions and the mineralization processes of bone tissue. Structural characterization indicated that the known IBSP/Sialoprotein II are glycoproteins ranging in their apparent molecular weights between 70 - 105 kDa.
ZJ25F0723675
危险品化学品经营许可证（带存储）