计算溶液所需的质量、体积或浓度。
Recombinant Human CCL18 Protein (rp143731) - Protein Bioactivity
The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 1.0-10 ng/mL.
ActiBioPure™,PBS Only,无叠氮钠,无载体,生物活性,高性能 级 提供 ≥96%(SDS-PAGE&HPLC) 纯度,适用于对基线干扰要求严格的色谱和分析工作流程。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Human CCL18 is encoded by the CCL18 gene located on the chromosome 17. As also named MIP-4, it shares 61 % sequence identity to human MIP-1α. CCL18 is mainly expressed by lung and some lymphoid tissues like lymph nodes express CCL18 at low level. It is chemotactic for both activated (CD3+) T cells and nonactivated (CD14-) lymphocytes, but not for monocytes or granulocytes. Involved in B-cell migration into B-cell follicles in lymph nodes. CCL18 plays a role in both humoral and cell mediated immunity responses. Recombinant Human MIP-4/CCL18 is a 7.9kDa protein containing 69 amino acid residues, including the four highly conserved cysteine residues present in CC chemokines.
Purity
>96% SDS-PAGE
Function
Chemotactic factor that attracts lymphocytes but not monocytes or granulocytes. May be involved in B-cell migration into B-cell follicles in lymph nodes. Attracts naive T-lymphocytes toward dendritic cells and activated macrophages in lymph nodes, has chemotactic activity for naive T-cells, CD4+ and CD8+ T-cells and thus may play a role in both humoral and cell-mediated immunity responses.
Recombinant Human CCL18 Protein (rp143731) - Protein Bioactivity
The biological activity determined by a chemotaxis bioassay using human T-lymphocytes is in a concentration of 1.0-10 ng/mL.
Recombinant Human CCL18 Protein (rp143731) - SDS-PAGE
2.5μg/lane of Recombinant Human CCL18 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 9.5 kDa under reducing conditions and 12.0 kDa under non-reducing conditions.
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | rp143731 | |
| 分析证书 | rp143731 | |
| 分析证书 | rp143731 | |
| 分析证书 | rp143731 | |
| 分析证书 | rp143731 | |
| 分析证书 | rp143731 |
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