Purity ≥95% (SDS-PAGE) Endotoxin level <0.1 EU/μg Function Receptor for the Fc region of complexed or aggregated immunoglobulins gamma. Low affinity receptor. Involved in a variety of effector and regulatory functions such as phagocytosis of immune complexes and modulation of antibody production by B-cells. Binding to this receptor results in down-modulation of previous state of cell activation triggered via antigen receptors on B-cells (BCR), T-cells (TCR) or via another Fc receptor. Isoform IIB1 fails to mediate endocytosis or phagocytosis. Isoform IIB2 does not trigger phagocytosis.
规格
产品名称
Recombinant Human Fc gamma RIIB/CD32b Protein
别名
IgG-Fc片段低亲和力受体Ⅱb(FcgR2B)重组蛋白
英文别名
CDw32 | Fc-gamma RII-b | Fc-gamma-RIIb | FcRII-b | IgG Fc receptor II-b | CD32 | CD32 antigen | CD32B | CDw32 | Fc fragment of IgG, low affinity II, receptor for (CD32) | Fc fragment of IgG, low affinity IIb, receptor | Fc fragment of IgG, low affinity II
27 - 32 kDa, under reducing conditions; 25 - 30 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH 7.4
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human Fc gamma RIIB/CD32b Protein (rp143962) - SDS-PAGE 3 μg/lane of Recombinant Human Fc gamma RIIB/CD32b Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 27 - 32 kDa under reducing conditions and 25 - 30 kDa under non-reducing conditions.