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Recombinant Human CD98 Protein (rp144163) - Protein Bioactivity
Immobilized Recombinant Human CD98 Protein (rp144163) at 5.0 μg/mL can bind ITGB1 with a linear range of 20 -1280 ng/mL. The EC₅₀ for this effect is 918.8 ng/mL.
ActiBioPure™,His标签,无动物源,无叠氮钠,无载体,生物活性 级 提供 ≥95%(SDS-PAGE) 纯度,适用于对基线干扰要求严格的色谱和分析工作流程。
-20°C储存,避免反复冻融。超低温运输 。请查阅批次 COA 获取详细规格。
SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。
在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Purity
≥95% (SDS-PAGE)
Endotoxin level
<0.1 EU/μg
Function
Required for the function of light chain amino-acid transporters. Involved in sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan. Involved in guiding and targeting of LAT1 and LAT2 to the plasma membrane. When associated with SLC7A6 or SLC7A7 acts as an arginine/glutamine exchanger, following an antiport mechanism for amino acid transport, influencing arginine release in exchange for extracellular amino acids. Plays a role in nitric oxide synthesis in human umbilical vein endothelial cells (HUVECs) via transport of L-arginine. Required for normal and neoplastic cell growth. When associated with SLC7A5/LAT1, is also involved in the transport of L-DOPA across the blood-brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in tissues such as placenta. Involved in the uptake of methylmercury (MeHg) when administered as the L-cysteine or D,L-homocysteine complexes, and hence plays a role in metal ion homeostasis and toxicity. When associated with SLC7A5 or SLC7A8, involved in the cellular activity of small molecular weight nitrosothiols, via the stereoselective transport of L-nitrosocysteine (L-CNSO) across the transmembrane. Together with ICAM1, regulates the transport activity LAT2 in polarized intestinal cells, by generating and delivering intracellular signals. When associated with SLC7A5, plays an important role in transporting L-leucine from the circulating blood to the retina across the inner blood-retinal barrier."
Recombinant Human CD98 Protein (rp144163) - Protein Bioactivity
Immobilized Recombinant Human CD98 Protein (rp144163) at 5.0 μg/mL can bind ITGB1 with a linear range of 20 -1280 ng/mL. The EC₅₀ for this effect is 918.8 ng/mL.
Recombinant Human CD98 Protein (rp144163) - SDS-PAGE
3 μg/lane of Recombinant Human CD98 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 55 - 65 kDa.
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | rp144163 | |
| 分析证书 | rp144163 | |
| 分析证书 | rp144163 | |
| 分析证书 | rp144163 | |
| 分析证书 | rp144163 | |
| 分析证书 | rp144163 |
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