Function The soluble form is chemotactic for T-cells and monocytes, but not for neutrophils. The membrane-bound form promotes adhesion of those leukocytes to endothelial cells. May play a role in regulating leukocyte adhesion and migration processes at the endothelium. Binds to CX3CR1.
Post-translational A soluble short 95 kDa form may be released by proteolytic cleavage from the long membrane-anchored form. O-glycosylated with core 1 or possibly core 8 glycans.
45 - 70 kDa, under reducing conditions; 45 - 70 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from PBS, pH 7.4, 5% trehalose, 5% mannitol
复溶
It is recommended to reconstitute the lyophilized protein in sterile H2O to a concentration not less than 100 μg/mL and incubate the stock solution for at least 20 min to ensure sufficient re-dissolved.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
-80℃~ -20℃ 12 个月,避免冷冻和解冻循环。
图片
Recombinant Human CX3CL1 Protein (rp144831) - Protein Bioactivity Measured by its ability to chemoattract BaF3 mouse pro‑B cells transfected with human CX3CR1. The ED₅₀ for this effect is 2.5 -10.0 ng/mL.
Recombinant Human CX3CL1 Protein (rp144831) - SDS-PAGE 3 μg/lane of Recombinant Human CX3CL1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 45 - 70 kDa.
Recombinant Human CX3CL1 Protein (rp144831) - ELISA Immobilized Recombinant Human CX3CL1 Protein (rp144831) at 1.0 μg/mL can bind Quetmolimab (anti-CX3CL1) (Ab177929) with the EC₅₀ of 41.08 ng/mL.