1. Measured by its ability to bind human NOTCH1 in a functional ELISA. 2. Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 2-20 μg/mL.
Purity >95% (SDS-PAGE) Endotoxin level <1.0 EU/μg Function Acts as a ligand for Notch receptors. Blocks the differentiation of progenitor cells into the B-cell lineage while promoting the emergence of a population of cells with the characteristics of a T-cell/NK-cell precursor. Post-translational Ubiquitinated by MIB (MIB1 or MIB2), leading to its endocytosis and subsequent degradation.
1. Measured by its ability to bind human NOTCH1 in a functional ELISA. 2. Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED50 for this effect is typically 2-20 μg/mL.
It is recommended that sterile water be added to the vial to prepare a stock solution of 0.25mg/mL.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20℃ 至 -80℃ 的无菌条件下保存。收货后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human DLL1 protein (rp145162) - Protein Bioactivity Measured by the ability of the immobilized protein to enhance BMP2-induced alkaline phosphatase activity in C3H10T1/2 mouse embryonic fibroblast cells. The ED₅₀ for this effect is typically 2 - 20 μg/mL.
Recombinant Human DLL1 protein (rp145162) - Protein Bioactivity Measured by its ability to bind human NOTCH1 in a functional ELISA. Immobilized Recombinant Human DLL1 protein (rp145162) at 2 μg/mL can bind human NOTCH1.
Recombinant Human DLL1 protein (rp145162) - SDS-PAGE 3 μg/lane of Recombinant Human DLL1 was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 61.1 kDa.