Measured by its binding ability in a functional ELISA. Immobilized rhEphB6/at 2 µg/mL (100 µL/well) can bind rmEphrin-B2/Fc Chimera with a linear range of 0.0780-5.00 ng/mL.
Kinase-defective receptor for members of the ephrin-B family. Binds to ephrin-B1 and ephrin-B2. Modulates cell adhesion and migration by exerting both positive and negative effects upon stimulation with ephrin-B2. Inhibits JNK activation, T cell receptor-induced IL-2 secretion and CD25 expression upon stimulation with ephrin-B2.
Post-translational:
Ligand-binding increases phosphorylation on tyrosine residues. Phosphorylation on tyrosine residues is mediated by transphosphorylation by the catalytically active EPHB1 in a ligand-independent manner. Tyrosine phosphorylation of the receptor may act as a switch on the functional transition from cell adhesion/attraction to de-adhesion/repulsion.
Measured by its binding ability in a functional ELISA. Immobilized rhEphB6/at 2 µg/mL (100 µL/well) can bind rmEphrin-B2/Fc Chimera with a linear range of 0.0780-5.00 ng/mL.
Recombinant Human EphB6 Protein (rp145625) - SDS-PAGE
2 μg/lane of Recombinant Human EphB6 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 69 kDa under reducing condition and 65 kDa under non-reducing condition.
ZJ26F1039847
危险品化学品经营许可证（带存储）