1. Measured in a cell proliferation assay using SH-SY5Y human neuroblastoma cells. The ED50 for this effect is typically 3-20 ng/mL in the presence of Recombinant Human GFR alpha-1/GDNF R alpha-1 His Chimera. 2. Immobilized Recombinant Human GDNF Protein at 2μg/mL (100 μL/well) can bind Recombinant Human GFRA1 / GFRα1/GDNFRA Protein (His Tag) , the EC50 is 15-48 ng/mL.
Purity ≥97% (SDS-PAGE) Endotoxin level <1.0 EU/μg Function Neurotrophic factor that enhances survival and morphological differentiation of dopaminergic neurons and increases their high-affinity dopamine uptake.
1. Measured in a cell proliferation assay using SH-SY5Y human neuroblastoma cells. The ED50 for this effect is typically 3-20 ng/mL in the presence of Recombinant Human GFR alpha-1/GDNF R alpha-1 His Chimera. 2. Immobilized Recombinant Human GDNF Protein at 2μg/mL (100 μL/well) can bind Recombinant Human GFRA1 / GFRα1/GDNFRA Protein (His Tag) , the EC50 is 15-48 ng/mL.
Recombinant Human GDNF Protein (rp146397) - Protein Bioactivity Immobilized Recombinant Human GDNF Protein (rp146397) at 2 μg/mL can bind biotinylated Recombinant Human GFRA1/GFRα1/GDNFRA Protein, the EC₅₀ is 15.0 - 48.0 ng/mL.
Recombinant Human GDNF Protein (rp146397) - SDS-PAGE 3 μg/lane of Recombinant Human GDNF Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 15.6 kDa under reducing conditions and 32.6 kDa under non-reducing conditions.