Measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons. Recombinant Human Progranulin/PGRN, immobilized at 10-40 μg/mL on a nitrocellulose coated plate, is able to significantly enhance neurite outgrowth.
Purity ≥92% (SDS-PAGE) Endotoxin level ＜0.1 EU/μg Function Granulins have possible cytokine-like activity. They may play a role in inflammation, wound repair, and tissue remodeling. Granulin-4 promotes proliferation of the epithelial cell line A431 in culture while granulin-3 acts as an antagonist to granulin-4, inhibiting the growth.
规格
产品名称
Recombinant Human Progranulin Protein
别名
颗粒体蛋白(GRN)重组蛋白
英文别名
Acrogranin | Epithelin precursor | Glycoprotein 88 | Glycoprotein of 88 Kda | GP88 | Granulin precursor | PC cell-derived growth factor | PCDGF | PEPI | PGRN | Proepithelin | Acrogranin | CLN11 | GEP | GP88 | Granulin A | Granulin B | Granulin C | Granuli
Measured by its ability to enhance neurite outgrowth of E16-E18 rat embryonic cortical neurons. Recombinant Human Progranulin/PGRN, immobilized at 10-40 μg/mL on a nitrocellulose coated plate, is able to significantly enhance neurite outgrowth.
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH 7.4
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human Progranulin Protein (rp146631) - SDS-PAGE 2 μg/lane of Recombinant Human Progranulin Protein was resolved with SDS-PAGE under reducing (R) conditions and visualized by Coomassie® Blue staining, showing the band at 70 - 90 kDa under reducing conditions.
ZJ25F0319858
危险品化学品经营许可证（带存储）