Ligand for the T-cell-specific cell surface receptor ICOS. Acts as a costimulatory signal for T-cell proliferation and cytokine secretion; induces also B-cell proliferation and differentiation into plasma cells. Could play an important role in mediating local tissue responses to inflammatory conditions, as well as in modulating the secondary immune response by co-stimulating memory T-cell function.
Reconstitute in water to a concentration of 0.1-1.0 mg/ml.
储存条件
-20°C储存
运输条件
超低温运输
稳定性与储存
在 -20~ -80℃ 下可保存 1 年以上。
图片
Recombinant Human B7-H2 Protein (rp147187) - Protein Bioactivity Immobilized Recombinant Human B7-H2 Protein (rp147187) at 1.0 μg/mL can bind Human ICOS/CD278 with a linear range of 2.0 -15.0 ng/mL.
Recombinant Human B7-H2 Protein (rp147187) - SDS-PAGE 3 μg/lane of Recombinant Human B7-H2 was resolved with SDS-PAGE under reducing (R) condition and visualized by Coomassie® Blue staining, showing the band at 43.1 - 55.3 kDa.