Transferrins are iron binding transport proteins which can bind two Fe(3+) ions in association with the binding of an anion, usually bicarbonate. Lactotransferrin has antimicrobial activity which depends on the extracellular cation concentration. Lactoferroxins A, B and C have opioid antagonist activity. Lactoferroxin A shows preference for mu-receptors, while lactoferroxin B and C have somewhat higher degrees of preference for kappa-receptors than for mu-receptors. The lactotransferrin transferrin-like domain 1 functions as a serine protease of the peptidase S60 family that cuts arginine rich regions. This function contributes to the antimicrobial activity.
80 kDa, under reducing conditions; 65 kDa, under non-reducing conditions.
作用类型
抑制剂
CAS编号和信息
146897-68-9
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Na2HPO3, NaH2PO3, NaCl, pH 5.2-7.2.
复溶
Reconstitute in sterile PBS to a concentration of 10 mg/ml. After dissolution, sterile OsrhLF can be stored at 4 ℃ for 1 month.
储存条件
2-8°C储存
运输条件
低温运输
稳定性与储存
在 2-8℃ 下保存 24 个月。收货后建议分装。
图片
Recombinant Human Lactoferrin Protein (rp148153) - SDS-PAGE 1 μg/lane of Recombinant Human Lactoferrin Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 80 kDa under reducing conditions and 65 kDa under non-reducing conditions.