≥90% (SDS-PAGE) Endotoxin level <0.1 EU/μg Function Arginase is the focal enzyme of the urea cycle hydrolysing L-arginine to urea and L-ornithine. Emerging studies have identified arginase in the vasculature and have implicated this enzyme in the regulation of nitric oxide (NO) synthesis and the development of vascular disease. Arginase also redirects the metabolism of L-arginine to L-ornithine and the formation of polyamines and L-proline, which are essential for smooth muscle cell growth and collagen synthesis. Arginase is encoded by two recently discovered genes (Arginase I and Arginase II). In most mammals, Arginase 1 (ARG1) also known as Arginase, liver, which functions in the urea cycle, and is located primarily in the cytoplasm of the liver. The second isozyme, Arginase II, has been implicated in the regulation of the arginine/ornithine concentrations in the cell. It is located in mitochondria of several tissues in the body, with most abundance in the kidney and prostate. It may be found at lower levels in macrophages, lactating mammary glands, and brain.
规格
产品名称
Recombinant Human Arginase 1/ARG1 Protein
别名
重组人肝精氨酸酶蛋白 | 重组人类精氨酸酶 1/ARG1 蛋白
英文别名
AI | ARG1 | Arginase 1 | Arginase, liver | Arginase-1 | EC 3.5.3.1 | Liver Arginase | Liver-type arginase | PGIF | Type I Arginase
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human Arginase 1/ARG1 (rp148330) - SDS-PAGE 3 μg/lane of Recombinant Human Arginase 1/ARG1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 38.0 kDa.