Measured by its ability to inhibit BMP-4-induced activity in MC3T3E1 mouse preosteoblast cells. The ED50 for this effect is 0.2-1 µg/mL in the presence of 50 ng/mL of rhBMP-4.
Function Possible candidate as a tumor suppressor gene of neuroblastoma. May play an important role in preventing cells from entering the final stage (G1/S) of the transformation process.
DAN domain family member 1 | DAN | DAND1 | MGC8972 | NBL1 | neuroblastoma suppressor of tumorigenicity 1 | neuroblastoma, suppression of tumorigenicity 1 | Protein N03 | suppression of tumorigenicity 1 | Zinc finger protein DAN | NB | NO3 | D1S1733E | DAN
Measured by its ability to inhibit BMP-4-induced activity in MC3T3E1 mouse preosteoblast cells. The ED50 for this effect is 0.2-1 µg/mL in the presence of 50 ng/mL of rhBMP-4.
25 kDa, under reducing conditions; 44 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH7.4.
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human DAN Protein (rp149100) - SDS-PAGE 3 μg/lane of Recombinant Human DAN Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 25 kDa under reducing condition and 44 kDa under non-reducing condition.