级别和纯度: 无动物源?无动物源(Animal Free)—— 不含动物源成分生产,降低污染风险。适用于避免动物源材料的生物制造和培养。无载体?无载体(Carrier Free)—— 不含添加的载体蛋白/稳定剂。当载体(如 BSA)会干扰偶联或敏感检测时使用。生物活性?生物活性级(Bioactive)—— 经验证在功能检测中保持生物活性。当分子须具有功能活性而不仅是纯度时使用。ActiBioPure™?ActiBioPure™ —— 阿拉丁面向生物活性和重组产品的优质系列。当同时需要高纯度和保持生物活性时使用。Fc标签?Fc 标签级 —— 带有 Fc 标签的重组蛋白,供亲和纯化/检测。用于纯化、固定或检测带标签蛋白。Fc 标签有助于二聚化和 protein A/G 捕获。≥95%(SDS-PAGE)
Accession #
Q6DKI7
蛋白标签
C-hFc
表达系统
HEK293
内毒素水平
<0.1 EU/μg
生物活性
Measured by its binding ability in a functional ELISA. When Recombinant Human PVRIG Fc Chimera is immobilized at 1 μg/mL, 100 μL/well, the concentration of Recombinant Human Nectin-2/CD112 that produces 50% of the optimal binding response is 0.4-2.4 μg/mL.
Cell surface receptor for NECTIN2. May act as a coinhibitory receptor that suppresses T-cell receptor-mediated signals. Following interaction with NECTIN2, inhibits T-cell proliferation. Competes with CD226 for NECTIN2-binding.
Measured by its binding ability in a functional ELISA. When Recombinant Human PVRIG Fc Chimera is immobilized at 1 μg/mL, 100 μL/well, the concentration of Recombinant Human Nectin-2/CD112 that produces 50% of the optimal binding response is 0.4-2.4 μg/mL.
Recombinant Human PVRIG Protein (rp150710) - Binding Activity Immobilized Recombinant Human PVRIG Protein (rp150710) at 2.0 μg/mL can bind Recombinant Human Nectin-2/CD112 Protein (rp149157) with the EC₅₀ of 1.09 μg/mL.
Recombinant Human PVRIG Protein (rp150710) - SDS-PAGE 2 μg/lane of Recombinant Human PVRIG Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 50 kDa under reducing condition and 95 kDa under non-reducing condition.