Measured by its ability to inhibit Wnt3a-induced alkaline phosphatase production by C3H10T 1/2 2A6 mouse embryonal fibroblast cells. The ED50 for this effect is typically 2-20 μg/mL in the presence of 20 ng/mL of Wnt3a.
Purity >95% SDS-PAGE. Function Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP4 may act as a regulator of adult uterine morphology and function. Increases apoptosis during ovulation possibly through modulation of FZ1/FZ4/WNT4 signaling (By similarity). Has phosphaturic effects by specifically inhibiting sodium-dependent phosphate uptake.
规格
产品名称
Recombinant Human SFRP4 Protein
别名
重组人SFRP4蛋白 | 重组人分泌型卷曲相关蛋白4 | 重组人 SFRP4 蛋白
英文别名
Frizzled protein | Frizzled protein human endometrium | FRP 4 | FRP4 | FrpHE | human endometrium | PYL | Secreted frizzled-related protein 4 | sFRP-4 | Sfrp4 | SFRP4_HUMAN | DDC-4 | Frizzled protein, human endometrium | FRP-4 | FRP-AP | FRPHEMGC26498 | Fr
Measured by its ability to inhibit Wnt3a-induced alkaline phosphatase production by C3H10T 1/2 2A6 mouse embryonal fibroblast cells. The ED50 for this effect is typically 2-20 μg/mL in the presence of 20 ng/mL of Wnt3a.
Recombinant Human SFRP4 Protein (rp151482) - Protein Bioactivity Measured by its ability to inhibit Wnt3a-induced alkaline phosphatase production by C3H10T 1/2 2A6 mouse embryonal fibroblast cells. The ED₅₀ for this effect is typically 2 - 20 μg/mL in the presence of 20 ng/mL of Wnt3a.
Recombinant Human SFRP4 Protein (rp151482) - SDS-PAGE 3 μg/lane of Recombinant Human SFRP4 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 60.0 kDa under reducing conditions and 57.0 kDa under non-reducing conditions.
ZJ23F1001332
危险品化学品经营许可证（带存储）