Measured by its ability to co-stimulate IL-4 secretion by D10.G4.1 mouse helper T cells in the presence of anti-CD3. The ED50 for this effect is 0.6-2.4 μg/mL.
Purity ≥95% SDS-PAGE. Endotoxin level <0.1 EU/µg Function High-affinity self-ligand important in bidirectional T-cell to B-cell stimulation. SLAM-induced signal-transduction events in T-lymphocytes are different from those in B-cells. Two modes of SLAM signaling are likely to exist: one in which the inhibitor SH2D1A acts as a negative regulator and another in which protein-tyrosine phosphatase 2C (PTPN11)-dependent signal transduction operates.
规格
产品名称
Recombinant Human SLAM/CD150 Protein
别名
重组人SLAM/CD150蛋白 | 重组人信号淋巴细胞激活分子家族成员1蛋白
英文别名
CDw150 | IPO-3 | SLAM family member 1 | Signaling Lymphocytic Activation Molecule | CD 150 | CD150 | CDw150 | IPO-3 | signaling lymphocytic activation molecule family member 1 | SLAM | CD150 antigen | SLAMF1
Measured by its ability to co-stimulate IL-4 secretion by D10.G4.1 mouse helper T cells in the presence of anti-CD3. The ED50 for this effect is 0.6-2.4 μg/mL.
45 - 60 kDa, under reducing conditions; 45 - 60 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH7.4.
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human SLAM/CD150 Protein (rp151608) - SDS-PAGE 3 μg/lane of Recombinant Human SLAM/CD150 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 45 - 60 kDa.
ZJ24F1214682
危险品化学品经营许可证（带存储）