Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit the cell growth of Mv1Lu mink lung epithelial cells is less than 3.0 μg/mL, corresponding to a specific activity of > 333 IU/mg.
Function Appears to regulate cell growth through interactions with the extracellular matrix and cytokines. Binds calcium and copper, several types of collagen, albumin, thrombospondin, PDGF and cell membranes. There are two calcium binding sites; an acidic domain that binds 5 to 8 Ca (2+) with a low affinity and an EF-hand loop that binds a Ca(2+) ion with a high affinity.
规格
产品名称
Recombinant Human SPARC Protein
别名
重组人SPARC蛋白 | 重组人 SPARC 蛋白
英文别名
ON | ONT | OI17 | BM-40 | Basement-membrane protein 40 | ONcysteine-rich protein | Osteonectin | Secreted protein acidic and rich in cysteine | secreted protein, acidic, cysteine-rich (osteonectin) | SPARC | AA517111 | Basement membrane protein 40 | BM 40
Fully biologically active when compared to standard. The ED50 as determined by its ability to inhibit the cell growth of Mv1Lu mink lung epithelial cells is less than 3.0 μg/mL, corresponding to a specific activity of > 333 IU/mg.
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute in sterile distilled water or aqueous buffer containing 0.1 % BSA to a concentration of 0.1-1.0 mg/mL. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
Recombinant Human SPARC Protein (rp151779)-Protein Bioactivity Fully biologically active when compared to standard. The ED₅₀ as determined by its ability to inhibit the cell growth of Mv1Lu mink lung epithelial cells is less than 3.0 μg/mL, corresponding to a specific activity of > 333 IU/mg.
Recombinant Human SPARC Protein (rp151779) - SDS-PAGE Recombinant Human SPARC Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie® Blue staining. Showing a single band at 32.7 kDa.