Lineage-specific cytokine affecting the proliferation and maturation of megakaryocytes from their committed progenitor cells. It acts at a late stage of megakaryocyte development. It may be the major physiological regulator of circulating platelets.
规格
产品名称
Recombinant Human Thrombopoietin Protein
别名
血小板生成素(TPO)重组蛋白 | 重组人血小板生成素蛋白
英文别名
Megakaryocyte colony-stimulating factor | Megakaryocyte growth and development factor | megakaryocyte stimulating factor | MGDF | MGDFC-mpl ligand | MKCSF | MK-CSF | ML | MPL ligand | MPLLG | MPLLGMGC163194 | Myeloproliferative leukemia virus oncogene lig
70-90 kDa, under reducing conditions; 70-90 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
biological_products
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Liquid PBS, pH 7.4, 5% Trehalose, 5% Mannitol
复溶
Reconstitute in sterile water to 0.1mg/ml. Centrifuge vial before opening. Suspend the product by gently pipetting the above recommended solution down the sides of the vial. DO NOT VORTEX. Allow several minutes for complete reconstitution. For prolonged storage, dilute to working aliquots in a 0.1% BSA solution, store at -80°C, and avoid repeat freeze thaws.
Recombinant Human Thrombopoietin Protein (rp152321) - Protein Bioactivity Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED₅₀ for this effect is typically less than 50 ng/mL.
Recombinant Human Thrombopoietin Protein (rp152321) - SDS-PAGE 2.5 μg/lane of Recombinant Human Thrombopoietin Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 70-90 kDa.