Purity >95% SDS-PAGE. Function Binds with high affinity to the poliovirus receptor (PVR) which causes increased secretion of IL10 and decreased secretion of IL12B and suppresses T cell activation by promoting the generation of mature immunoregulatory dendritic cells.
规格
产品名称
Recombinant Human TIGIT Protein
别名
重组人TIGIT蛋白 | 重组人TIGIT蛋白
英文别名
T cell immunoreceptor with Ig and ITIM domains | TIGIT | VSIG9 | VSTM3 | WUCAM | V-set and immunoglobulin domain-containing protein 9 | V-set and transmembrane domain-containing protein 3
17.0 kDa, under reducing conditions; 17.0 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
biological_products
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 1×PBS, PH7.4, containing 5% trehalose, 5% mannitol
复溶
Reconstitute in sterile H2O to a concentration of 0.1-0.5 mg/ml.
储存条件
-80℃储存,避免反复冻融
运输条件
特低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。
图片
Recombinant Human TIGIT Protein - Protein Bioactivity Immobilized Human TIGIT (rp152378) at 1.5 μg/mL can bind Human CD155 with a linear range of 0.15 - 1.2 μg/mL.
Recombinant Human TIGIT Protein (rp152378) - SDS-PAGE 2.5 μg/lane of Recombinant Human TIGIT was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 17.0 kDa.
Recombinant Human TIGIT Protein (rp152378) - ELISA Immobilized Recombinant Human TIGIT Protein (rp152378) at 1.0 μg/mL can bind Domvanalimab (anti-TIGIT) (Ab182911) with the EC₅₀ of 15.97 ng/mL.
Recombinant Human TIGIT Protein (rp152378) - ELISA Immobilized Recombinant Human TIGIT Protein (rp152378) at 1.0 μg/mL can bind Ociperlimab (anti-TIGIT) (Ab182915) with the EC
₅₀
of 120.2 ng/mL.