级别和纯度: 无动物源?无动物源(Animal Free)—— 不含动物源成分生产,降低污染风险。适用于避免动物源材料的生物制造和培养。无载体?无载体(Carrier Free)—— 不含添加的载体蛋白/稳定剂。当载体(如 BSA)会干扰偶联或敏感检测时使用。生物活性?生物活性级(Bioactive)—— 经验证在功能检测中保持生物活性。当分子须具有功能活性而不仅是纯度时使用。ActiBioPure™?ActiBioPure™ —— 阿拉丁面向生物活性和重组产品的优质系列。当同时需要高纯度和保持生物活性时使用。高性能?高性能级 —— 纯度和性能特性经过优化。适用于普通等级无法满足的灵敏分析。His标签?组氨酸(His) 标签级 —— 带有 His 标签的重组蛋白,供亲和纯化/检测。用于纯化、固定或检测带标签蛋白。Fc标签?Fc 标签级 —— 带有 Fc 标签的重组蛋白,供亲和纯化/检测。用于纯化、固定或检测带标签蛋白。Fc 标签有助于二聚化和 protein A/G 捕获。≥90%(SDS-PAGE)
Accession #
Q6UWB1
蛋白标签
C-hFc & His
表达系统
HEK293
内毒素水平
<0.1 EU/μg
生物活性
Measured by its ability to inhibit IL-27 anti-viral activity using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. The ED50 for this effect is 0.754.5 µg/mL.
Function Receptor for IL27. Requires IL6ST/gp130 to mediate signal transduction in response to IL27. This signaling system acts through STAT3 and STAT1. Involved in the regulation of Th1-type immune responses. Also appears to be involved in innate defense mechanisms.
规格
产品名称
Recombinant Human IL-27 Ra/WSX-1/TCCR Protein
别名
重组人IL-27 Ra/WSX-1/TCCR蛋白 | 重组人白介素27受体α蛋白
英文别名
Cytokine receptor WSX-1 | Cytokine receptor-like 1 | IL-27 receptor subunit alpha | IL-27R subunit alpha | IL-27RA | IL-27R-alpha | TCCR | Type I T-cell cytokine receptor | ZcytoR1 | class I cytokine receptor | CRL1 | IL-27R | Cytokine receptor-like 1 | I
Measured by its ability to inhibit IL-27 anti-viral activity using HepG2 human hepatocellular carcinoma cells infected with encephalomyocarditis (EMC) virus. The ED50 for this effect is 0.754.5 µg/mL.
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH7.4
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。复溶后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human IL-27 Ra/WSX-1/TCCR Protein (rp153308) - SDS-PAGE 2 μg/lane of Recombinant Human IL-27 Ra/WSX-1/TCCR Protein was resolved with SDS-PAGE under reducing (R) conditions and visualized by Coomassie® Blue staining, showing the band at 100 - 110 kDa under reducing conditions.