Measured by its ability to cleave a fluorogenic peptide substrate, Mca-YVADAPK(Dnp)-OH. The specific activity is >400 pmol/min/µg, as measured under the described conditions.
Function Carboxypeptidase which converts angiotensin I to angiotensin 1-9, a peptide of unknown function, and angiotensin II to angiotensin 1-7, a vasodilator. Also able to hydrolyze apelin-13 and dynorphin-13 with high efficiency. May be an important regulator of heart function. In case of human coronaviruses SARS and HCoV-NL63 infections, serve as functional receptor for the spike glycoprotein of both coronaviruses.
规格
产品名称
Recombinant Mouse ACE-2 Protein
别名
血管紧张素转化酶2(ACE2)活性蛋白
英文别名
ACE-2 | ACE2 | ACEH | ACEHangiotensin I converting enzyme 2 | ACE-related carboxypeptidase | angiotensin I converting enzyme (peptidyl-dipeptidase A) 2 | angiotensin-converting enzyme 2 | Angiotensin-converting enzyme homolog | DKFZp434A014 | EC 3.4.17 |
规格或纯度
无动物源,无载体,生物活性,ActiBioPure™,His标签,≥95%(SDS-PAGE)
生物活性
Measured by its ability to cleave a fluorogenic peptide substrate, Mca-YVADAPK(Dnp)-OH. The specific activity is >400 pmol/min/µg, as measured under the described conditions.
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH 7.4
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。复溶后建议分装。避免冷冻/解冻循环。
图片
Recombinant Mouse ACE-2 Protein (rp153552) - SDS-PAGE 2 μg/lane of Recombinant Mouse ACE-2 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 100 kDa.