Measured by its ability to enhance IL-6 secretion by human peripheral blood mononuclear cells (PBMC). The ED50 for this effect is typically 0.8-4 µg/mL
Purity ≥95% (SDS-PAGE) Endotoxin level <1.0 EU/μg Function C3 plays a central role in the activation of the complement system. Its processing by C3 convertase is the central reaction in both classical and alternative complement pathways. After activation C3b can bind covalently, via its reactive thioester, to cell surface carbohydrates or immune aggregates. Derived from proteolytic degradation of complement C3, C3a anaphylatoxin is a mediator of local inflammatory process. It induces the contraction of smooth muscle, increases vascular permeability and causes histamine release from mast cells and basophilic leukocytes.
规格
产品名称
Recombinant Mouse Complement Component C3a Protein
别名
补体成分3(C3)重组蛋白
英文别名
Acylation stimulating protein cleavage product | AHUS5 | ARMD9 | ASP | C3 and PZP like alpha 2 macroglobulin domain containing protein 1 | C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1 | c3 complement | C3adesArg | Complement C3 | Complement C3 alpha chain | Complement C3b alpha' chain | Complement C3c alpha' chain fra 展开
Measured by its ability to enhance IL-6 secretion by human peripheral blood mononuclear cells (PBMC). The ED50 for this effect is typically 0.8-4 µg/mL
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH 7.4
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。复溶后建议分装。避免冷冻/解冻循环。
图片
Recombinant Mouse Complement Component C3a Protein (rp153647) - SDS-PAGE
2 μg/lane of Recombinant Mouse Complement Component C3a Protein was resolved with SDS-PAGE under reducing (R) condition and visualized by Coomassie® Blue staining, showing the band at 11 kDa under reducing condition.
ZJ26F1039853
危险品化学品经营许可证（带存储）