This product is for the mature full length protein. The signal peptide is not included. NP_033971
Function
Cooperates with MD-2 and TLR4 to mediate the innate immune response to bacterial lipopolysaccharide (LPS). Acts via MyD88, TIRAP and TRAF6, leading to NF-kappa-B activation, cytokine secretion and the inflammatory response. Up-regulates cell surface molecules, including adhesion molecules.
Post-translational
N- and O- glycosylated. O-glycosylated with a core 1 or possibly core 8 glycan.
规格
产品名称
Recombinant Mouse CD14 Protein
别名
重组小鼠单核细胞分化抗原CD14蛋白 | 重组小鼠CD14蛋白
英文别名
CD 14 | CD_antigen=CD14 | CD14 | CD14 antigen | CD14 molecule | CD14_HUMAN | LPS-R | Mo2 | Monocyte differentiation antigen CD14 | Monocyte differentiation antigen CD14 urinary form | Monocyte differentiation antigen CD14, membrane-bound form | Myeloid ce
Recombinant Mouse CD14 Protein (rp153710) - Protein Bioactivity Measured by its ability to enhance LPS-induced IL-6 secretion by mouse splenocytes. The ED₅₀ for this effect is 2.2 µg/mL.
Recombinant Mouse CD14 Protein (rp153710) - SDS-PAGE 2 μg/lane of Recombinant Mouse CD14 was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 85.5 kDa under reducing conditions and 195.7 kDa under non-reducing conditions.