计算溶液所需的质量、体积或浓度。
Recombinant Mouse IL-13 Protein (rp154139)-Protein Bioactivity
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED₅₀ for this effect is typically <4ng/mL.
ActiBioPure™,PBS Only,无动物源,无叠氮钠,无载体,生物活性,高性能 级 提供 ≥98%(SDS-PAGE&HPLC) 纯度,适用于对基线干扰要求严格的色谱和分析工作流程。
-20°C储存,避免反复冻融。超低温运输 。请查阅批次 COA 获取详细规格。
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在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。
Murine Interleukin-13 (IL-13) is expressed by the IL13 gene located on the chromosome 11 and secreted by many cell types, especially T helper type 2 (Th2) cells. Targeted deletion of IL-13 in mice resulted in impaired Th2 cell development and indicated an important role for IL-13 in the expulsion of gastrointestinal parasites. IL-13 exerts anti-inflammatory effects on monocytes and macrophages and it inhibits the expression of inflammatory cytokines such as IL-1β, TNF-α, IL-6 and IL-8. IL-13 has also been shown to enhance B cell proliferation and to induce isotype switching, resulting in increased production of IgE. Blocking of IL-13 activity inhibits the pathophysiology of asthma. Human, mouse and rat IL-13 share low homology, but have cross species activity. Recombinant Murine IL-13 is a 12.3kDa protein consisting of 111 amino acid residues
Purity
>98%(SDS-PAGE,HPLC)
Function
Cytokine. Inhibits inflammatory cytokine production. Synergizes with IL2 in regulating interferon-gamma synthesis. May be critical in regulating inflammatory and immune responses . Positively regulates IL31RA expression in macrophages.
Recombinant Mouse IL-13 Protein (rp154139)-Protein Bioactivity
Measured in a cell proliferation assay using TF‑1 human erythroleukemic cells. The ED₅₀ for this effect is typically <4ng/mL.
Recombinant Mouse IL-13 Protein (rp154139)-SDS-PAGE
3μg/lane of Recombinant Mouse IL-13 was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a single band at 11.2 kDa.
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| 批号(Lot Number) | 证书类型 | 货号 |
|---|---|---|
| 分析证书 | rp154139 | |
| 分析证书 | rp154139 | |
| 分析证书 | rp154139 | |
| 分析证书 | rp154139 | |
| 分析证书 | rp154139 |
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