Participates in at least several B-cell activation processes as well as of other cell types. It is a costimulator of DNA-synthesis. It induces the expression of class II MHC molecules on resting B-cells. It enhances both secretion and cell surface expression of IgE and IgG1. It also regulates the expression of the low affinity Fc receptor for IgE (CD23) on both lymphocytes and monocytes.
生物活性
Measured in a cell proliferation assay using assay using CTLL‑2 mouse cytotoxic T cells. The ED₅₀ for this effect is typically <1.8ng/mL.
Reconstitute in sterile H2O at not less than 100µg/ml, which can then be further diluted in other aqueous solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20℃ 下保存 1 年。收货后建议分装。避免冷冻/解冻循环。
图片
Recombinant Mouse IL-4 Protein (rp154228)-Protein Bioactivity Measured in a cell proliferation assay using assay using CTLL‑2 mouse cytotoxic T cells. The ED₅₀ for this effect is typically <1.8ng/mL.
Recombinant Mouse IL-4 Protein(rp154228)-SDS-PAGE 3μg/lane of Recombinant Mouse IL-4 was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 18.2 kDa.
Recombinant Mouse IL-4 Protein (rp154228) - Protein Bioactivity Measured in a cell proliferation assay using assay using NFS-60 mouse myelogenous leukemia lymphoblast cells. The ED₅₀ for this effect is typically <1.8 ng/mL.