Measured by its ability to compete with Frizzled-1 for binding to biotinylated Wnt-3a. The IC50 value is 0.7-3.5 nM, under conditions in which Recombinant Mouse (rm) Frizzled 1 Fc Chimera is present at 2.1 nM, and biotinylated rmWnt-3a concentration is 2.7 nM.
Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.
生物活性
Measured by its ability to compete with Frizzled-1 for binding to biotinylated Wnt-3a. The IC50 value is 0.7-3.5 nM, under conditions in which Recombinant Mouse (rm) Frizzled 1 Fc Chimera is present at 2.1 nM, and biotinylated rmWnt-3a concentration is 2.7 nM.
Lyophilized from 50mM Tris 250mM NaCl, 5% Trehalose, 5% Mannitol, pH8.0.
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
长期储存-20~-80℃（1年）；复溶后建议分装，避免反复冻融。
图片
Recombinant Mouse sFRP-2 Protein (rp154655) - SDS-PAGE 2 μg/lane of Recombinant Mouse sFRP-2 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 34 kDa under reducing conditions and 30 kDa under non-reducing conditions.
ZJ25F1028714
危险品化学品经营许可证（带存储）