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340,000+ 科研产品 · 三重ISO认证 · 每个产品均提供COA和SDS · 现货产品当日发货

Recombinant Human Bax Protein

Name: Recombinant Human Bax Protein
SKU: rp156638
Availability: InStock

货号: rp156638

COA

有货

级别和纯度: 无载体 ? PBS Only ? ≥90%(SDS-PAGE)

Accession #

Q07812

蛋白标签

No tag

表达系统

E. coli

内毒素水平

<1.0 EU/μg

规格

库存

价格

数量

10μg

rp156638-10μg

现货

¥999.90

50μg

rp156638-50μg

现货

¥2,999.90

100μg

rp156638-100μg

现货

¥4,799.90

1mg

rp156638-1mg

期货

¥14,999.90

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规格储存与运输图片技术文档高级数据质检证书（CoA,COO,BSE/TSE 和分析图谱) 溶液计算器

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为什么选择此级别

PBS Only,无载体级提供 ≥90%(SDS-PAGE) 纯度，适用于对基线干扰要求严格的色谱和分析工作流程。

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储存与运输

-20°C储存,避免反复冻融。超低温运输。请查阅批次 COA 获取详细规格。

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质量文档

SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。

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文献证明

在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。

规格

产品名称

Recombinant Human Bax Protein

别名

重组人Bax蛋白 | 重组人凋亡调节蛋白BAX蛋白

英文别名

Apoptosis regulator BAX | Bcl-2-like protein 4 | Bcl2-L-4 | BAX | BCL2L4

规格或纯度

无载体, PBS Only, ≥90%(SDS-PAGE)

生化机理

Plays a role in the mitochondrial apoptotic process (PubMed:10772918, PubMed:11060313, PubMed:16113678, PubMed:16199525, PubMed:18948948, PubMed:21199865, PubMed:21458670, PubMed:25609812, PubMed:36361894, PubMed:8358790, PubMed:8521816). Under normal conditions, BAX is largely cytosolic via constant retrotranslocation from mitochondria to the cytosol mediated by BCL2L1/Bcl-xL, which avoids accumulation of toxic BAX levels at the mitochondrial outer membrane (MOM) (PubMed:21458670). Under stress conditions, undergoes a conformation change that causes translocation to the mitochondrion membrane, leading to the release of cytochrome c that then triggers apoptosis (PubMed:10772918, PubMed:11060313, PubMed:16113678, PubMed:16199525, PubMed:18948948, PubMed:21199865, PubMed:21458670, PubMed:25609812, PubMed:8358790, PubMed:8521816). Promotes activation of CASP3, and thereby apoptosis (PubMed:10772918, PubMed:11060313, PubMed:16113678, PubMed:16199525, PubMed:18948948, PubMed:21199865, PubMed:21458670, PubMed:25609812, PubMed:8358790, PubMed:8521816). Post-translational: Ubiquitinated on Lys-128 and Lys-190. 'Lys-63'-linked polyubiquitin chains on Lys-128 are removed by USP12.

表达系统

E. coli

种属

人(Human)

氨基酸

2-171 aa

序列

GDGSGEQPRGGGPTSSEQIMKTGALLLQGFIQDRAGRMGGEAPELALDPVPQDASTKKLSECLKRIGDELDSNMELQRMIAAVDTDSPREVFFRVAADMFSDGNFNWGRVVALFYFASKLVLKALCTKVPELIRTIMGWTLDFLRERLLGWIQDQGGWDGLLSYFGTPTWQ

蛋白标签

No tag

无载体

Yes

无动物源

来源

重组表达

预测分子量

18.9 kDa

SDS-PAGE

16.5 kDa, under reducing conditions; 16.0 & 37.0 kDa, under non-reducing conditions.

分子类型

蛋白质

产品线

生物产品

储存与运输

物理形态

冻干(Lyophilized)

储存缓冲液

Lyophilized from PBS, pH 7.4

复溶

We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.

储存条件

-20°C储存,避免反复冻融

运输条件

超低温运输

稳定性与储存

Store at -20°C for 1 year. Avoid freeze/thaw cycle.

图片

SDS-PAGE: Recombinant Human Bax Protein (rp156638)

Recombinant Human Bax Protein (rp156638) - SDS-PAGE
3 μg/lane of Recombinant Human Bax Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 16.5 kDa under reducing conditions and 16.0 & 37.0 kDa under non-reducing conditions.