| 货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
|---|---|---|---|---|
| rp156646-10μg (试用装) 申请此免费试用装（?） 作为尊贵的客户，您每年可免费申请一次试用装产品，尽享探索与享受！
|
10μg |
现货  |
| |
| rp156646-100μg |
100μg |
现货 |
| |
| rp156646-1mg |
1mg |
现货 |
|
| 产品名称 | Recombinant Human SOX2 Protein |
|---|---|
| 别名 | 重组人SOX2蛋白 | 重组人 SOX2 蛋白 |
| 英文别名 | cb236 | Delta EF2a | Lcc | MCOPS3 | MGC148683 | MGC2413 | RGD1565646 | Sex determining region Y box 2 | ANOP3 | SOX 2 | Sox2 | SOX2_HUMAN | SRY (sex determining region Y) box 2 | SRY box containing gene 2 | SRY related HMG box 2 | SRY related HMG box gene |
| 规格或纯度 | Carrier Free, ≥90%(SDS-PAGE) |
| 产品介绍 |
SOX2 is a member of the SOXB1 subfamily of transcription factors most notably involved in the reprogramming of somatic cells into induced pluripotent stem cells. Housed on chromosome 3, the SOX2 gene encodes for a protein with a C-terminal transcriptional activation domain and a DNA-binding HMG domain that contains a nuclear localization/export signal. SOX2 forms a trimeric complex with OCT4 on DNA and controls the expression of a number of genes involved in embryonic development and pluripotency such as YES1, FGF4, UTF1 and ZFP206. Mutations in this gene have been associated with bilateral eye disease. SOX2 antigen and antibody were found in small-cell lung cancer cell lines and sera. However, neither exists in normal sera, suggesting that SOX2 might be a potential tumor target or marker. |
| 内毒素水平 | <1.0 EU/μg |
| 表达系统 | E. coli |
| 氨基酸 | 1-317 aa |
| 序列 | MGHHHHHHMYNMMETELKPPGPQQTSGGGGGNSTAAAAGGNQKNSPDRVKRPMNAFMVWSRGQRRKMAQENPKMHNSEISKRLGAEWKLLSETEKRPFIDEAKRLRALHMKEHPDYKYRPRRKTKTLMKKDKYTLPGGLLAPGGNSMASGVGVGAGLGAGVNQRMDSYAHMNGWSNGSYSMMQDQLGYPQHPGLNAHGAAQMQPMHRYDVSALQYNSMTSSQTYMNGSPTYSMSYSQQGTPGMALGSMGSVVKSEASSSPPVVTSSSHSRAPCQAGDLRDMISMYLPGAEVPEPAAPSRLHMSQHYQSGPVPGTAINGTLPLSHMESGGGGSPGRRRRRRRRRRR |
| 蛋白标签 | N-His |
| 无载体 | Yes |
| 无动物源 | No |
| Accession # | P48431 |
| 来源 | 重组表达 |
| 预测分子量 | 37.3 kDa |
| SDS-PAGE | 37.3 kDa, under reducing conditions; 37.3 kDa, under non-reducing conditions |
Recombinant Human SOX2 Protein (rp156646) - SDS-PAGE
3 μg/lane of Recombinant Human SOX2 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 37.3 kDa.
| 物理形态 | 冻干(Lyophilized) |
|---|---|
| 储存缓冲液 | Lyophilized from 20mM Tris, 500mM NaCl, 8M Urea, 10mM imidazole, pH 8.0 |
| 复溶 | We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions. |
| 储存温度 | -20°C储存,避免反复冻融 |
| 运输条件 | 超低温冰袋运输 |
| 稳定性与储存 | 在 -20°C 下可保存 1 年。避免冷冻/解冻循环。 |
| 分子类型 | 蛋白质 |
通过匹配包装上的批号来查找并下载产品的 COA，每批产品都进行了严格的验证，您可放心使用！
| 批号(Lot Number) | 证书类型 | 日期 | 货号 |
|---|---|---|---|
 ZJ24F0809457 |
分析证书 | 24-08-14 | rp156646 |
| ZJ24F0809456 |
分析证书 | 24-08-14 | rp156646 |
| ZJ24F0809455 |
分析证书 | 24-08-14 | rp156646 |
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