Purity:>90%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description: Aurora-B, previously known as AIM-1, is a conserved eukaryotic mitotic protein kinase. In mammals, this kinase plays an essential role in chromosomal segregation processes, including chromosome condensation, alignment, control of spindle checkpoints, chromosome segregation, and cytokinesis. Aurora-B is overexpressed in various cancer cells, suggesting that the kinase activity perturbs chromosomal segregation processes. Its forced overexpression induces chromosomal number instability and progressive tumorigenicity in rodent cells in vitro and in vivo.
规格
产品名称
Recombinant Human Aurora B Protein
别名
重组人Aurora B/AIM1蛋白 | 重组人 Aurora B 蛋白
英文别名
AIK2AIM-1 | AIM1 | ARK-2 | ARK2 | AurB | AURKB | AURKB_HUMAN | Aurora 1 | Aurora and Ipl1 like midbody associated protein 1 | Aurora kinase B | Aurora related kinase 2 | Aurora- and Ipl1-like midbody-associated protein 1 | Aurora-B | Aurora-related kinase
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20°C 下可稳定保存 1 年。避免冷冻/解冻循环。
图片
Recombinant Human Aurora B/AIM1 protein (rp156680) - SDS-PAGE Recombinant Human Aurora B/AIM1 protein was resolved with SDS-PAGE under reducing (R) conditions and visualized by Coomassie® Blue staining, showing a band at 41.8 kDa.