Measured by its binding ability in a functional ELISA. Immoblized Recombinant Human BMP-4 Protein at 1 µg/mL can bind Recombinant Human RGM-B Protein (rp166982) with a linear range of 10 - 500 ng/mL and the EC50 for this effect is 232.0 ng/mL.
Member of the repulsive guidance molecule (RGM) family that contributes to the patterning of the developing nervous system (By similarity). Acts as a bone morphogenetic protein (BMP) coreceptor that potentiates BMP signaling (By similarity). Promotes neuronal adhesion (By similarity). May inhibit neurite outgrowth.
规格
产品名称
Recombinant Human RGM-B Protein
别名
重组人RGM-B蛋白 | 重组人反义导向分子B蛋白
英文别名
Repulsive Guidance Molecule B | DKFZp434P228 | Dragon | DRG11-responsive axonal guidance and outgrowth of neurite | RGM domain family, member B | RGMB | RGM-B
规格或纯度
无动物源,无载体,生物活性,ActiBioPure™,His标签,≥90%(SDS-PAGE)
生物活性
Measured by its binding ability in a functional ELISA. Immoblized Recombinant Human BMP-4 Protein at 1 µg/mL can bind Recombinant Human RGM-B Protein (rp166982) with a linear range of 10 - 500 ng/mL and the EC50 for this effect is 232.0 ng/mL.
18 kDa (N-terminus chain) and 35 kDa (C-terminus chain), under reducing conditions; 45 kDa (Full-length protein), under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH7.4.
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human RGM-B Protein (rp166982) - Protein Bioactivity Measured by its binding ability in a functional ELISA. Immoblized Recombinant Human BMP-4 Protein at 1 µg/mL can bind Recombinant Human RGM-B Protein (rp166982) with a linear range of 10 - 500 ng/mL and the EC50 for this effect is 232.0 ng/mL.
Recombinant Human RGM-B Protein (rp166982) - SDS-PAGE 2 μg/lane of Recombinant Human RGM-B Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 18 kDa (N-terminus chain) and 35 kDa (C-terminus chain) under reducing conditions and 45 kDa (Full-length protein) under non-reducing conditions.