Purity ≥95% (SDS-PAGE) Endotoxin level <0.1 EU/μg Function The protein encoded by the SIRPß1 gene is a member of the signal-regulatory-protein (SIRP) family, and also belongs to the immunoglobulin superfamily. SIRP family members are receptor-type transmembrane glycoproteins which are known to be involved in the negative regulation of receptor tyrosine kinase-coupled signaling processes. SIRPß1 was found to interact with TYROBP/DAP12, a protein bearing immunoreceptor tyrosine-based activation motifs. This protein was also reported to participate in the recruitment of tyrosine kinase SYK. Multiple transcript variants encoding different isoforms have been found for this gene.
规格
产品名称
Recombinant Human SIRP beta 1/CD172b Protein
别名
信号调节蛋白β1(SIRPb1)重组蛋白 | 重组人 SIRP beta 1/CD172b 蛋白
英文别名
CD172 antigen like family member B | CD172b | CD172b antigen | DKFZp686A05192 | Signal regulatory protein beta 1 | SIRP BETA 1 | SIRP beta 1 isoform 3 | SIRPB1 | SIRP-BETA-1
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH 7.4
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human SIRP beta 1/CD172b Protein (rp167082) - Protein Bioactivity When Recombinant Human SIRP beta 1/CD172b Protein (rp167082) is immobilized at 1.0 µg/mL, Recombinant Human SP‑D binds with an ED₅₀ of 0.93 μg/mL.
Recombinant Human SIRP beta 1/CD172b Protein (rp167082) - SDS-PAGE 3 μg/lane of Recombinant Human SIRP beta 1/CD172b Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 45.0 - 55.0 kDa.