Recombinant Human IL-17A/F Heterodimer Protein

功能和特点
  • 表达系统: HEK293
  • Accession #: Q16552,Q96PD4
  • 蛋白标签: C-His (IL17F)
  • 生物活性: Measured by its ability to induce IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.4‑2 ng/mL.
  • 内毒素水平: <0.1 EU/μg
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货号 (SKU) 包装规格 是否现货 价格 数量
rp167375-10μg
10μg 现货 Stock Image
rp167375-50μg
50μg 现货 Stock Image
rp167375-100μg
100μg 现货 Stock Image
rp167375-1mg
1mg 期货 Stock Image

基本描述

产品名称 Recombinant Human IL-17A/F Heterodimer Protein
别名 重组人IL-17A/F蛋白
英文别名 CTLA8cytotoxic T-lymphocyte-associated serine esterase 8 | Cytotoxic T-lymphocyte-associated antigen 8 | Cytotoxic T-Lymphocyte-Associated Protein 8 | IL17 | IL-17 | IL-17A | IL-17A/F Heterodimer | interleukin 17 (cytotoxic T-lymphocyte-associated serine
规格或纯度 ActiBioPure™, Bioactive, Animal Free, Carrier Free, High performance, ≥95%(SDS-PAGE)
产品介绍


Relevance:
IL-17F stimulates the production of other cytokines such as IL-6, IL-8 and granulocyte colony-stimulating factor, and can regulate cartilage matrix turnover. Stimulates PBMC and T-cell proliferation. Inhibits angiogenesis. IL-17A induces stromal cells to produce proinflammatory and hematopoietic cytokines. Enhances the surface expression of the intracellular adhesion molecule-1 (ICAM-1) in fibroblasts.

生物活性 Measured by its ability to induce IL-6 secretion by NIH‑3T3 mouse embryonic fibroblast cells. The ED50 for this effect is 0.4‑2 ng/mL.
内毒素水平 <0.1 EU/μg
表达系统 HEK293
种属 人(Human)
氨基酸 24-155 aa (IL17A)&31-163 aa (IL17F)
序列 IL17A: GITIPRNPGCPNSEDKNFPRTVMVNLNIHNRNTNTNPKRSSDYYNRSTSPWNLHRNEDPERYPSVIWEAKCRHLGCINADGNVDYHMNSVPIQQEILVLRREPPHCPNSFRLEKILVSVGCTCVTPIVHHVA IL17F: RKIPKVGHTFFQKPESCPPVPGGSMKLDIGIINENQRVSMSRNIESRSTSPWNYTVTWDPNRYPSEVVQAQCRNLGCINAQGKEDISMNSVPIQQETLVVRRKHQGCSVSFQLEKVLVTVGCTCVTPVIHHVQHHHHHH
蛋白标签 C-His (IL17F)
无载体 Yes
无动物源 Yes
Accession # Q16552,Q96PD4
来源 重组表达
预测分子量 31 kDa
SDS-PAGE 16 - 23 kDa, under reducing conditions; 35 - 42 kDa, under non-reducing conditions.

AI解读

图片

Recombinant Human IL-17A/F Heterodimer Protein (rp167375) - SDS-PAGE
2 μg/lane of Recombinant Human IL-17A/F Heterodimer Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 16 - 23 kDa under reducing condition and 35 - 42 kDa under non-reducing condition.

产品规格参数

物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH7.4.
复溶 Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -20~-80℃ 下可保存 1 年以上。收货后建议分装。避免冷冻/解冻循环。
分子类型 蛋白质

技术规格说明书

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找到3个结果

批号(Lot Number) 证书类型 日期 货号
ZJ25F0420757 分析证书 25-04-25 rp167375
ZJ25F0420758 分析证书 25-04-25 rp167375
ZJ25F0420759 分析证书 25-04-25 rp167375

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