Measured by its ability to synergize with Wnt-3a to induce Topflash reporter activity in HEK293T human embryonic kidney cells. The ED50 for this effect is 10-40 ng/mL in the presence of 20 ng/mL of Recombinant Mouse Wnt‑3a.
Function Soluble frizzled-related proteins (sFRPS) function as modulators of Wnt signaling through direct interaction with Wnts. They have a role in regulating cell growth and differentiation in specific cell types. SFRP2 may be important for eye retinal development and for myogenesis.
规格
产品名称
Recombinant Human sFRP-2 Protein
别名
重组人sFRP-2蛋白 | 重组人分泌型卷曲相关蛋白2蛋白
英文别名
FRP2 | FRP-2 | secreted apoptosis related protein 1 | SARP-1 | SARP1s | SDF-5 | Secreted apoptosis-related protein 1 | secreted frizzled-related protein 2 | sFRP2 | sFRP-2 | SARP1
Measured by its ability to synergize with Wnt-3a to induce Topflash reporter activity in HEK293T human embryonic kidney cells. The ED50 for this effect is 10-40 ng/mL in the presence of 20 ng/mL of Recombinant Mouse Wnt‑3a.
Lyophilized from 10mM PBS, 5% Trehalose, 5% Mannitol, pH7.4.
复溶
Reconstitute in sterile water to a concentration of 0.1-0.5 mg/ml.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20~-80℃ 下可保存 1 年以上。复溶后建议分装。避免冷冻/解冻循环。
图片
Recombinant Human sFRP-2 Protein (rp168329) - SDS-PAGE 2 μg/lane of Recombinant Human sFRP-2 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing the band at 33 kDa under reducing conditions and 28 kDa under non-reducing conditions.