EL52 | epididymis luminal secretory protein 52 | Heat shock 86 kDa | heat shock 90kD protein 1, alpha | Heat shock 90kD protein 1, alpha like 4 | heat shock 90kD protein, alpha-like 4 | Heat shock 90kDa protein 1 alpha | Heat shock protein 90kDa alpha (cy
规格或纯度
无载体, His标签, ≥80%(SDS-PAGE), 见COA
生化机理
Heat shock protein HSP 90-alpha (HSP90AA1 or HSP90A) is also known as Heat shock 86 kDa (HSP 86 or HSP86), Renal carcinoma antigen NY-REN-38, HSPC1, HSPCA, EL52, HSP89A, HSP90N, HSPCAL1, HSPCAL4, HSPN, Hsp89, Hsp90, LAP2, which belongs to the heat shock protein 90 family. HSP90AA1 undergoes a functional cycle that is linked to its ATPase activity. This cycle probably induces conformational changes in the client proteins, thereby causing their activation. HSP90AA1 interacts dynamically with various co-chaperones that modulate its substrate recognition, ATPase cycle and chaperone function.
Post-translational: ISGylated.S-nitrosylated; negatively regulates the ATPase activity and the activation of eNOS by HSP90AA1. Ubiquitinated via 'Lys-63'-linked polyubiquitination by HECTD1. Ubiquitination promotes translocation into the cytoplasm away from the membrane and secretory pathways.
88.0 kDa, under reducing conditions; 84.8 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
液体
储存缓冲液
PBS, 5% Glycerol, pH 7.4
浓度
见COA
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
-20℃ 存储12个月；收货后建议分装，避免反复冻融。
图片
Recombinant Human Hsp90 alpha Protein (rp169626) - SDS-PAGE 2 μg/lane of Recombinant Human Hsp90 alpha Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 88.0 kDa under reducing conditions and 84.8 kDa under non-reducing conditions.
ZJ25F0927962
危险品化学品经营许可证（带存储）