Immobilized Recombinant Human 4-1BB/TNFRSF9 Protein (rp169624) at 2.0 μg/mL can bind Recombinant Human 4-1BB Ligand/TNFSF9 Protein (rp169691) with the EC50 of 6.053 ng/mL.
Purity:≥95%, by SDS-PAGE visualized with Coomassie® Blue Staining. Description： 4-1BB ligand is the high affinity ligand of 4-1BB, also known as CD137L or TNFSF9. It is shown to be a type II surface glycoprotein belonging to the TNF superfamily. Expression of 4-1BBL is restricted to APCs, such as dendritic cells, macrophages, and activated B cells. Members of the TNF-TNF receptor superfamily have been shown to play critical roles in regulating cellular activation, differentiation and apoptosis. Several studies have reported that 4-1BBL/4-1BB interaction provided a co-stimulatory signal to T cells, and increased T cell proliferation and cytokines production. In addition, 4-1BBL is involved in cancers, infectious diseases and autoimmune diseases.
Immobilized Recombinant Human 4-1BB/TNFRSF9 Protein (rp169624) at 2.0 μg/mL can bind Recombinant Human 4-1BB Ligand/TNFSF9 Protein (rp169691) with the EC50 of 6.053 ng/mL.
20.6 kDa, under reducing conditions; 20.6 kDa, under non-reducing conditions
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from PBS, 300mM NaCl, 3% trehalose, pH7.4
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.1 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
图片
Recombinant Human 4-1BB Ligand/TNFSF9 Protein (rp169691) - ELISA
Measured by its binding ability in a functional ELISA. Immobilized Human 4-1BB Ligand/TNFSF9 Protein (rp169691) at 2.0 μg/mL can bind Human 4-1BB Ligand/TNFSF9-biotin with the EC₅₀ of 6.053 ng/mL.
Recombinant Human 4-1BB Ligand/TNFSF9 Protein (rp169691) - SDS-PAGE 2 μg/lane of Recombinant Human 4-1BB Ligand/TNFSF9 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 20.6 kDa.
ZJ24F0809686
危险品化学品经营许可证（带存储）