计算溶液所需的质量、体积或浓度。
活性类型 | 活性值-log(M) | 作用机制 | 期刊 | 参考文献(PubMed IDs) |
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货号 (SKU) | 包装规格 | 是否现货 | 价格 | 数量 |
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rp173490-500μg |
500μg |
期货 ![]() |
| |
rp173490-1mg |
1mg |
期货 ![]() |
|
产品名称 | APRIL, B 细胞成熟抗原;TACI |
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别名 | A proliferation-inducing ligand;TALL2;TNF- and APOL-related leukocyte expressed ligand 2;TNF-related death ligand 1;TRDL-1;ZTNF2 |
英文别名 | A proliferation-inducing ligand;TALL2;TNF- and APOL-related leukocyte expressed ligand 2;TNF-related death ligand 1;TRDL-1;ZTNF2 |
规格或纯度 | Moligand™ |
作用机制 | B 细胞成熟抗原;TACI |
CAS编号和信息 | rp173490 |
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1. Wu Y, Bressette D, Carrell JA, Kaufman T, Feng P, Taylor K, Gan Y, Cho YH, Garcia AD, Gollatz E et al.. (2000) Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS.. J Biol Chem, 275 (45): (35478-85). [PMID:10956646] [10.1021/op500134e] |
2. López-Fraga M, Fernández R, Albar JP, Hahne M. (2001) Biologically active APRIL is secreted following intracellular processing in the Golgi apparatus by furin convertase.. EMBO Rep, 2 (10): (945-51). [PMID:11571266] [10.1021/op500134e] |
3. Belnoue E, Pihlgren M, McGaha TL, Tougne C, Rochat AF, Bossen C, Schneider P, Huard B, Lambert PH, Siegrist CA. (2008) APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells.. Blood, 111 (5): (2755-64). [PMID:18180376] [10.1021/op500134e] |
4. Samy E, Wax S, Huard B, Hess H, Schneider P. (2017) Targeting BAFF and APRIL in systemic lupus erythematosus and other antibody-associated diseases.. Int Rev Immunol, 36 (1): (3-19). [PMID:28215100] [10.1021/op500134e] |
5. Cogollo E, Cogollo E, Silva MA, Isenberg D. (2015) Profile of atacicept and its potential in the treatment of systemic lupus erythematosus.. Drug Des Devel Ther, 9 (13): (1331-9). [PMID:25834391] [10.1021/op500134e] |
6. Hahne M, Kataoka T, Schröter M, Hofmann K, Irmler M, Bodmer JL, Schneider P, Bornand T, Holler N, French LE et al.. (1998) APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth.. J Exp Med, 188 (6): (1185-90). [PMID:9743536] [10.1021/op500134e] |