APRIL, B 细胞成熟抗原;TACI

功能和特点
有货

库存信息

关闭

库存信息

关闭
货号 (SKU) 包装规格 是否现货 价格 数量
rp173490-500μg
500μg 期货 Stock Image
rp173490-1mg
1mg 期货 Stock Image

基本描述

产品名称 APRIL, B 细胞成熟抗原;TACI
别名 A proliferation-inducing ligand;TALL2;TNF- and APOL-related leukocyte expressed ligand 2;TNF-related death ligand 1;TRDL-1;ZTNF2
英文别名 A proliferation-inducing ligand;TALL2;TNF- and APOL-related leukocyte expressed ligand 2;TNF-related death ligand 1;TRDL-1;ZTNF2
规格或纯度 Moligand™
作用机制 B 细胞成熟抗原;TACI

AI解读

关联靶点(人)

TNFRSF13B Tbio 肿瘤坏死因子受体超家族成员 13B(Tumor necrosis factor receptor superfamily member 13B) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)
TNFRSF17 Tclin 肿瘤坏死因子受体超家族成员 17(Tumor necrosis factor receptor superfamily member 17) (0 活性数据)
活性类型 活性值-log(M) 作用机制 期刊 参考文献(PubMed IDs)

产品规格参数

CAS编号和信息 rp173490

质检证书(CoA,COO,BSE/TSE 和分析图谱)

C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

参考文献

1. Wu Y, Bressette D, Carrell JA, Kaufman T, Feng P, Taylor K, Gan Y, Cho YH, Garcia AD, Gollatz E et al..  (2000)  Tumor necrosis factor (TNF) receptor superfamily member TACI is a high affinity receptor for TNF family members APRIL and BLyS..  J Biol Chem,  275  (45): (35478-85).  [PMID:10956646] [10.1021/op500134e]
2. López-Fraga M, Fernández R, Albar JP, Hahne M.  (2001)  Biologically active APRIL is secreted following intracellular processing in the Golgi apparatus by furin convertase..  EMBO Rep,  (10): (945-51).  [PMID:11571266] [10.1021/op500134e]
3. Belnoue E, Pihlgren M, McGaha TL, Tougne C, Rochat AF, Bossen C, Schneider P, Huard B, Lambert PH, Siegrist CA.  (2008)  APRIL is critical for plasmablast survival in the bone marrow and poorly expressed by early-life bone marrow stromal cells..  Blood,  111  (5): (2755-64).  [PMID:18180376] [10.1021/op500134e]
4. Samy E, Wax S, Huard B, Hess H, Schneider P.  (2017)  Targeting BAFF and APRIL in systemic lupus erythematosus and other antibody-associated diseases..  Int Rev Immunol,  36  (1): (3-19).  [PMID:28215100] [10.1021/op500134e]
5. Cogollo E, Cogollo E, Silva MA, Isenberg D.  (2015)  Profile of atacicept and its potential in the treatment of systemic lupus erythematosus..  Drug Des Devel Ther,  (13): (1331-9).  [PMID:25834391] [10.1021/op500134e]
6. Hahne M, Kataoka T, Schröter M, Hofmann K, Irmler M, Bodmer JL, Schneider P, Bornand T, Holler N, French LE et al..  (1998)  APRIL, a new ligand of the tumor necrosis factor family, stimulates tumor cell growth..  J Exp Med,  188  (6): (1185-90).  [PMID:9743536] [10.1021/op500134e]

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