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Recombinant Human ALDH1A1 Protein

功能和特点
  • 表达系统: E. coli
  • Accession #: P00352
  • 蛋白标签: N-His
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货号 (SKU) 包装规格 是否现货 价格 数量
rp175922-10μg (试用装)
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 		10μg 现货 Stock Image
rp175922-100μg
 100μg 现货 Stock Image
rp175922-1mg
 1mg 现货 Stock Image
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点击查看蛋白信息: ALDH1A1
Accession#:P00352 (6) ALDH1A1 (6) Gene ID:216 (6)
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基本描述

产品名称 Recombinant Human ALDH1A1 Protein
别名 重组人ALDH1A1蛋白 | 重组人 ALDH1A1 蛋白
英文别名 Aldehyde dehydrogenase family 1 member A1 | Aldehyde dehydrogenase, cytosolic | ALDH-E1 | ALHDII | EC 1.2.1.- | EC 1.2.1.36 | RALDH 1 | RalDH1 | acetaldehyde dehydrogenase 1 | ALDC | aldehyde dehydrogenase 1 family, member A1 | aldehyde dehydrogenase 1, s
规格或纯度 Carrier Free, Azide Free, ≥95%(SDS-PAGE)
产品介绍


Purity:>95%, by SDS-PAGE visualized with Coomassie® Blue Staining.
Description：
Aldehyde dehydrogenase 1 family, member A1 (ALDH1A1), also known as Aldehyde dehydrogenase 1 (ALDH1), or Retinaldehyde Dehydrogenase 1 (RALDH1), is an enzyme that is expressed at high levels in stem cells and that has been suggested to regulate stem cell function. The retinaldehyde dehydrogenase (RALDH) subfamily of ALDHs, composed of ALDH1A1, ALDH1A2, ALDH1A3, and ALDH8A1, regulate development by catalyzing retinoic acid biosynthesis. The ALDH1A1 protein belongs to the aldehyde dehydrogenases family of proteins. Aldehyde dehydrogenase is the second enzyme of the major oxidative pathway of alcohol metabolism. ALDH1A1 also belongs to the group of corneal crystallins that help maintain the transparency of the cornea. Increased ALDH1A1 activity has been found in the stem cell populations of leukemia and some solid tumors. In tumor specimens, increased ALDH1A1 immunopositivity was found not only in secretory type cancer epithelial cells but also in neuroendocrine tumor populations. ALDH1 has been identified as a reliable marker of breast cancer stem cells. ALDH1 expression in primary cancer is an independent prognostic factor in node-positive breast cancer patients. ALDH1A1 plays a key role in normal hematopoiesis, and as a TLX1 transcriptional target, ALDH1A1 may contribute to the ability of this homeoprotein to alter cell fate and induce tumor growth.
表达系统 E. coli
种属 人(Human)
氨基酸 2-501 aa
序列 MHHHHHHSSSGTPDLPVLLTDLKIQYTKIFINNEWHDSVSGKKFPVFNPATEEELCQVEEGDKEDVDKAVKAARQAFQIGSPWRTMDASERGRLLYKLADLIERDRLLLATMESMNGGKLYSNAYLNDLAGCIKTLRYCAGWADKIQGRTIPIDGNFFTYTRHEPIGVCGQIIPWNFPLVMLIWKIGPALSCGNTVVVKPAEQTPLTALHVASLIKEAGFPPGVVNIVPGYGPTAGAAISSHMDIDKVAFTGSTEVGKLIKEAAGKSNLKRVTLELGGKSPCIVLADADLDNAVEFAHHGVFYHQGQCCIAASRIFVEESIYDEFVRRSVERAKKYILGNPLTPGVTQGPQIDKEQYDKILDLIESGKKEGAKLECGGGPWGNKGYFVQPTVFSNVTDEMRIAKEEIFGPVQQIMKFKSLDDVIKRANNTFYGLSAGVFTKDIDKAITISSALQAGTVWVNCYGVVSAQCPFGGFKMSGNGRELGEYGFHEYTEVKTVTVKISQKNS
纯度 >95% (SDS-PAGE)
蛋白标签 N-His
无载体 Yes
无动物源 No
Accession # P00352
来源 重组表达
预测分子量 55.7 kDa
SDS-PAGE 55.1 kDa, reducing conditions; 55.1 kDa, non-reducing conditions

AI解读

图片

Recombinant Human ALDH1A1 Protein (rp175922) - SDS-PAGE
3 μg/lane of Recombinant Human ALDH1A1 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 55.1 kDa.

产品规格参数

物理形态 冻干(Lyophilized)
储存缓冲液 Lyophilized from PBS, pH7.4
复溶 We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存温度 -20°C储存,避免反复冻融
运输条件 超低温冰袋运输
稳定性与储存 在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
分子类型 蛋白质

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找到2个结果

批号(Lot Number) 证书类型 日期 货号
ZJ24F0202706 分析证书 24-02-06 rp175922
ZJ24F0202707 分析证书 24-02-06 rp175922

参考文献

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