Recombinant Human MMP-1 Protein

货号: rp176239
有货
级别和纯度: 无动物源 ? 无动物源(Animal Free)—— 不含动物源成分生产,降低污染风险。适用于避免动物源材料的生物制造和培养。 无载体 ? 无载体(Carrier Free)—— 不含添加的载体蛋白/稳定剂。当载体(如 BSA)会干扰偶联或敏感检测时使用。 生物活性 ? 生物活性级(Bioactive)—— 经验证在功能检测中保持生物活性。当分子须具有功能活性而不仅是纯度时使用。 ActiBioPure™ ? ActiBioPure™ —— 阿拉丁面向生物活性和重组产品的优质系列。当同时需要高纯度和保持生物活性时使用。 无叠氮钠 ? 无叠氮(Azide Free)—— 不含叠氮化钠防腐剂。适用于叠氮有毒或有抑制作用的偶联、细胞工作或检测。 His标签 ? 组氨酸(His) 标签级 —— 带有 His 标签的重组蛋白,供亲和纯化/检测。用于纯化、固定或检测带标签蛋白。 ≥95%(SDS-PAGE)
Accession #
P03956
蛋白标签
C-His
表达系统
HEK293
内毒素水平
<1.0 EU/μg
生物活性
Immobilized Recombinant Human MMP-1 Protein (rp176239) at 1.0 μg/mL can bind MMP1 Antibody (Ab115600) with the EC50 of 4.016 ng/mL.
★
规格
库存
价格
数量
10μg
rp176239-10μg
现货 Stock Image
¥899.90
50μg
rp176239-50μg
现货 Stock Image
¥2,899.90
100μg
rp176239-100μg
现货 Stock Image
¥4,499.90
1mg
rp176239-1mg
期货 Stock Image
¥16,999.90
请输入您要添加的产品数量
🧪
为什么选择此级别

ActiBioPure™,His标签,无动物源,无叠氮钠,无载体,生物活性 级 提供 ≥95%(SDS-PAGE) 纯度,适用于对基线干扰要求严格的色谱和分析工作流程。

🌡

储存与运输

-20°C储存,避免反复冻融。超低温运输 。请查阅批次 COA 获取详细规格。

📋

质量文档

SDS、COA、产品数据表及规格说明书均可下载。可通过批号查询获取批次 COA。

📚

文献证明

在色谱分析、有机合成和交叉偶联反应领域已被 0 篇同行评审文献引用。

概述


Purity: ≥95%, by SDS-PAGE visualized with Coomassie® Blue Staining.
Description:
MMP1, also known as MMP-1, contains 4 hemopexin-like domains and is a member of the matrix metalloproteinase (MMP) family. Matrix metalloproteases, also called matrixins, are zinc-dependent endopeptidases that are the major proteases involved in ECM degradation. MMPs are capable of degrading a wide range of extracellular molecules and some bioactive molecules. MMP activity is regulated by two major endogenous inhibitors: alpha2-macroglobulin and tissue inhibitors of metalloproteases (TIMPs). MMPs play a central role in cell proliferation, migration, differentiation, angiogenesis, apoptosis, and host defenses. Dysregulation of MMPs has been implicated in many diseases including arthritis, chronic ulcers, encephalomyelitis, and cancer. Tumour metastasis is a multistep process involving the dissemination of tumor cells from the primary tumor to secondary at a distant organ or tissue. One of the first steps in metastasis is the degradation of the basement membrane, a process in which MMPs have been implicated. MMPs are secreted by tumor cells themselves or by surrounding stromal cells stimulated by the nearby tumor. Numerous studies have linked altered MMP expression in different human cancers with poor disease prognosis. MMP-1, -2, -3, -7, -9, -13 and -14 all have elevated expression in primary tumors and/or metastases. MMP-1 cleaves collagens of types I, II, and III at one site in the helical domain. It also cleaves collagens of types VII and X. In case of HIV infection, MMP1 interacts and cleaves the secreted viral Tat protein, leading to a decrease in neuronal Tat's mediated neurotoxicity.

规格

产品名称
Recombinant Human MMP-1 Protein
别名
重组人MMP-1蛋白 | 重组人基质金属蛋白酶-1 | 重组人MMP-1蛋白
英文别名
CLGmatrix metalloprotease 1 | CLGN | Fibroblast collagenase | interstitial collagenase | matrix metallopeptidase 1 (interstitial collagenase) | matrix metalloproteinase 1 (interstitial collagenase) | Matrix metalloproteinase-1 | MMP-1 CLG Protein | CLGN P
规格或纯度
无动物源, 无载体, 生物活性, ActiBioPure™, 无叠氮钠, His标签, ≥95%(SDS-PAGE)
生物活性
Immobilized Recombinant Human MMP-1 Protein (rp176239) at 1.0 μg/mL can bind MMP1 Antibody (Ab115600) with the EC50 of 4.016 ng/mL.
表达系统
HEK293
种属
人(Human)
氨基酸
20-469 aa
序列
FPATLETQEQDVDLVQKYLEKYYNLKNDGRQVEKRRNSGPVVEKLKQMQEFFGLKVTGKPDAETLKVMKQPRCGVPDVAQFVLTEGNPRWEQTHLTYRIENYTPDLPRADVDHAIEKAFQLWSNVTPLTFTKVSEGQADIMISFVRGDHRDNSPFDGPGGNLAHAFQPGPGIGGDAHFDEDERWTNNFREYNLHRVAAHELGHSLGLSHSTDIGALMYPSYTFSGDVQLAQDDIDGIQAIYGRSQNPVQPIGPQTPKACDSKLTFDAITTIRGEVMFFKDRFYMRTNPFYPEVELNFISVFWPQLPNGLEAAYEFADRDEVRFFKGNKYWAVQGQNVLHGYPKDIYSSFGFPRTVKHIDAALSEENTGKTYFFVANKYWRYDEYKRSMDPGYPKMIAHDFPGIGHKVDAVFMKDGFFYFFHGTRQYKFDPKTKRILTLQKANSWFNCRKNHHHHHH
纯度
>95% (SDS-PAGE)
蛋白标签
C-His
N-末端序列
Phe20
无载体
Yes
无动物源
Yes
来源
重组表达
预测分子量
52.7 kDa
SDS-PAGE
51.9-56.0 kDa, under reducing conditions
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from 25 mM MES, 150 mM NaCl, pH 6.0
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 1.0 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
图片

Recombinant Human MMP-1 Protein (rp176239) - ELISA
Immobilized Recombinant Human MMP-1 Protein (rp176239) at 1.0 μg/mL can bind MMP1 Antibody (Ab115600) with the EC50 of 4.016 ng/mL.


Recombinant Human MMP-1 Protein (rp176239) - SDS-PAGE
3 μg/lane of Recombinant Human MMP-1 Protein was resolved with SDS-PAGE under reducing (R) and visualized by Coomassie® Blue staining, showing a band at 51.9-56.0 kDa.

技术文档

📋 安全数据表 (SDS)

全面的危险、操作、储存及法规合规文件。

下载 SDS →

✅ 分析证书 (COA)

批次质量数据。输入批号以获取对应 COA。

查询 COA →

📊 产品数据表

产品规格和应用的快速参考摘要。

查看数据表 →

🔬 规格说明书

该级别的完整质量属性和验收标准。

查看规格说明 →

高级数据

质检证书(CoA,COO,BSE/TSE 和分析图谱)
C of A & Other Certificates(BSE/TSE, COO):
输入批号以搜索分析图谱:

通过匹配包装上的批号来查找并下载产品的 COA,每批产品都进行了严格的验证,您可放心使用!

找到3个结果

批号(Lot Number) 证书类型 货号
ZJ24F0102689 分析证书 rp176239
ZJ24F0102690 分析证书 rp176239
ZJ24F0102691 分析证书 rp176239
技术文档和文章
溶液计算器