1. Immobilized Recombinant Human CD79B Protein (rp176729) at 1.0 μg/mL can bind Polatuzumab (anti-CD79b) (Ab175715) with the EC50 of 11.08 ng/mL. 2. Immobilized Recombinant Human CD79B Protein (rp176729) at 1.0 μg/mL can bind Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) with the EC50 of 51.95 ng/mL.
Required in cooperation with CD79A for initiation of the signal transduction cascade activated by the B-cell antigen receptor complex (BCR) which leads to internalization of the complex, trafficking to late endosomes and antigen presentation. Enhances phosphorylation of CD79A, possibly by recruiting kinases which phosphorylate CD79A or by recruiting proteins which bind to CD79A and protect it from dephosphorylation.
规格
产品名称
Recombinant Human CD79B Protein
别名
重组人CD79B蛋白 | 重组人 CD79B 蛋白
英文别名
B cell antigen receptor complex associated protein beta chain | B cell specific glycoprotein B29 | B-cell antigen receptor complex-associated protein beta chain | B-cell-specific glycoprotein B29 | B29 | B29/Ig-beta/CD79b | CD 79b | CD79b | CD79b antigen
1. Immobilized Recombinant Human CD79B Protein (rp176729) at 1.0 μg/mL can bind Polatuzumab (anti-CD79b) (Ab175715) with the EC50 of 11.08 ng/mL. 2. Immobilized Recombinant Human CD79B Protein (rp176729) at 1.0 μg/mL can bind Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) with the EC50 of 51.95 ng/mL.
26.8-38.0 kDa, under reducing conditions; 28.8-34.6 kDa, under non-reducing conditions
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from PBS, pH 7.4
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
图片
Recombinant Human CD79B Protein (rp176729) - ELISA Immobilized Recombinant Human CD79B Protein (rp176729) at 1.0 μg/mL can bind Polatuzumab (anti-CD79b) (Ab175715) with the EC₅₀ of 11.08 ng/mL.
Recombinant Human CD79B Protein (rp176729) - ELISA Immobilized Recombinant Human CD79B Protein (rp176729) at 1.0 μg/mL can bind Polatuzumab vedotin-piiq (anti-CD79b) (Ab175635) with the EC₅₀ of 51.95 ng/mL.
Recombinant Human CD79B Protein (rp176729) - SDS-PAGE 3 μg/lane of Recombinant Human CD79B Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 26.8-38.0 kDa under reducing conditions and 28.8-34.6 kDa under non-reducing conditions.