Protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. May down-regulate CTNNB1 levels and thereby modulate the Wnt pathway.
Post-translational: Polyubiquitinated; which leads to proteasomal degradation.
26.0 & 51.0 kDa, under reducing conditions; 26.0 & 51.0 kDa, under non-reducing conditions.
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
液体
储存缓冲液
50mM Hepes, 50% Glycerol, pH 7.4
浓度
见COA
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
图片
Recombinant Human SENP2 Protein (rp179788) - SDS-PAGE 3 μg/lane of Recombinant Human SENP2 Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 26.0 kDa under reducing conditions and 30.2 & 55.0 kDa under non-reducing conditions.
SENP2 appears to have the ability to form dimers under certain conditions (PMID: 38551331).