Protein Function: CXADR (coxsackie virus and adenovirus receptor), also known as CAR, is a type I transmembrane glycoprotein belonging to the CTX family of the Ig superfamily, and is essential for normal cardiac development in the mouse. Proposed as a homophilic cell adhesion molecule, CXADR is a component of the epithelial apical junction complex that is essential for the tight junction integrity, and probably involved in transepithelial migration of polymorphonuclear leukocytes (PMN). Mature mouse CXADR structrually comprises a 218 aa extracellular domain (ECD) with a V-type (D1) and a C2-type (D2) Ig-like domain, a 21 aa transmembrane segment and a 17 aa intracellular domain, among which,D1 is thought to be responsible for homodimer formation in trans within tight junctions. The ECD of mouse CXADR shares 97%, 9% sequence identity with the corresponding regions of rat, human CXADR.
规格
产品名称
Recombinant Human CXADR Protein
别名
重组人CXADR蛋白 | 重组人 CXADR 蛋白
英文别名
CAR4/6 | coxsackie virus and adenovirus receptor | coxsackie virus B receptor | coxsackievirus and adenovirus receptor | CVB3 binding protein | CVB3 BP | CVB3-binding protein | CXADR | HCAR | HCVADR | CAR10Coxsackievirus B-adenovirus receptor
29.0-34.0 kDa, under reducing conditions; 24.0-30.0 kDa, under non-reducing conditions
分子类型
蛋白质
产品线
生物产品
储存与运输
物理形态
冻干(Lyophilized)
储存缓冲液
Lyophilized from PBS, pH 7.4
复溶
We recommend that this vial be briefly centrifuged prior to opening to bring the contents to the bottom. Reconstitute at 0.5 mg/mL in sterile distilled water. Stock solutions should be apportioned into working aliquots and stored at ≤ -20 °C. Further dilutions should be made in appropriate buffered solutions.
储存条件
-20°C储存,避免反复冻融
运输条件
超低温运输
稳定性与储存
在 -20°C 下可保存 1 年。避免冷冻/解冻循环。
图片
Recombinant Human CXADR Protein (rp183611) - SDS-PAGE 3 μg/lane of Recombinant Human CXADR Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 29.0-34.0 kDa under reducing conditions and 24.0-30.0 kDa under non-reducing conditions.
ZJ24F0708019
危险品化学品经营许可证（带存储）