2A9 | 5B10 | CABP | CACY | Calcyclin | Growth factor inducible protein 2A9 | Growth factor-inducible protein 2A9 | MLN 4 | MLN4 | OTTHUMP00000015472 | OTTHUMP00000015473 | PRA | PRA Growth factor inducible protein 2A9 | Prolactin receptor associated prote
规格或纯度
无载体, ≥95%(SDS-PAGE), 见COA
生化机理
S100 protein is a family of low molecular weight protein found in vertebrates characterized by two EF-hand calcium-binding motifs. There are at least 21 different S100 proteins, and the name is derived from the fact that the protein is 100% soluble in ammonium sulfate at neutral pH. Most S100 proteins are disulfide-linked homodimer, and is normally present in cells derived from the neural crest, chondrocytes, macrophages, dendritic cells, etc. S100 proteins have been implicated in a variety of intracellular and extracellular functions. They are involved in regulation of protein phosphorylation, transcription factors, the dynamics of cytoskeleton constituents, enzyme activities, cell growth and differentiation, and the inflammatory response. S100A6 (S100 calcium-binding protein A6) is a member of the S100 family of proteins, and functions in prolactin secretion, and exocytosis. Chromosomal rearrangements and altered expression of S100A6 have been implicated in melanoma. May function as calcium sensor and modulator, contributing to cellular calcium signaling. May function by interacting with other proteins, such as TPR-containing proteins, and indirectly play a role in many physiological processes such as the reorganization of the actin cytoskeleton and in cell motility. Binds 2 calcium ions. Calcium binding is cooperative.
Post-translational: The N-terminus is blocked.
Store at -20°C for 1 year. Avoid freeze/thaw cycle.
图片
Recombinant Human S100 alpha 6/PRA Protein (rp183702) - SDS-PAGE 3 μg/lane of Recombinant Human S100 alpha 6/PRA Protein was resolved with SDS-PAGE under reducing (R) and non-reducing (N) conditions and visualized by Coomassie® Blue staining, showing a band at 10.1 kDa.
ZJ24F1113837
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